Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Nikolaou Plastira 100, Heraklion 70013, Crete, Greece.
Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Nikolaou Plastira 100, Heraklion 70013, Crete, Greece
Open Biol. 2018 Jun;8(6). doi: 10.1098/rsob.180049.
Multisensory integration is a mechanism that allows organisms to simultaneously sense and understand external stimuli from different modalities. These distinct signals are transduced into neuronal signals that converge into decision-making neuronal entities. Such decision-making centres receive information through neuromodulators regarding the organism's physiological state and accordingly trigger behavioural responses. Despite the importance of multisensory integration for efficient functioning of the nervous system, and also the implication of dysfunctional multisensory integration in the aetiology of neuropsychiatric disease, little is known about the relative molecular mechanisms. is an appropriate model system to study such mechanisms and elucidate the molecular ways through which organisms understand external environments in an accurate and coherent fashion.
多感觉整合是一种机制，使生物体能够同时感知和理解来自不同感觉模式的外部刺激。这些不同的信号被转导成神经元信号，这些信号汇聚到决策神经元实体中。这些决策中心通过神经调质接收有关生物体生理状态的信息，并相应地触发行为反应。尽管多感觉整合对于神经系统的有效运作非常重要，而且多感觉整合功能障碍在神经精神疾病的发病机制中也有一定的影响，但对于相对分子机制知之甚少。果蝇是研究这些机制的合适模型系统，可以阐明生物体以准确和连贯的方式理解外部环境的分子途径。
