Yamaguchi K, Yul L S, Shimizu T, Nozawa F, Takeya M, Takahashi K, Takatsuki K
Cancer. 1985 Oct 1;56(7):1688-90. doi: 10.1002/1097-0142(19851001)56:7<1688::aid-cncr2820560736>3.0.co;2-o.
Three sisters, ranging in age from 56 to 59 years, who developed lymphoma type adult T-cell leukemia (ATL) during a 19-month period are described. The patients were born in the Amakusa area of Kumamoto Prefecture, an area where the incidence of malignant lymphoma is high. The histologic diagnosis, made on the basis of the Lymphoma Study Group in Japan (LSG) classification of lymph nodes, was diffuse, medium-sized cell type in the elder sister, and mixed cell type in the middle and younger sisters. The patients and their elder brother had serum antibodies against ATL-associated antigens (ATLA).
本文描述了三姐妹，年龄在56岁至59岁之间，她们在19个月内均患上了成人T细胞白血病（ATL）淋巴瘤型。这些患者出生于熊本县天草地区，该地区恶性淋巴瘤发病率较高。根据日本淋巴瘤研究组（LSG）的淋巴结分类进行的组织学诊断显示，大姐为弥漫性中等细胞型，二姐和小妹为混合细胞型。这些患者及其大哥均有抗ATL相关抗原（ATLA）的血清抗体。
