Rafienia Mohammad, Bigham Ashkan, Hassanzadeh-Tabrizi Seyed Ali
Biosensor Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Advanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
J Med Signals Sens. 2018 Apr-Jun;8(2):108-118.
At present, solvothermal fabrication method has widely been applied in the synthesis of spinel ferrite nanoparticles (SFNs), which is mainly because of its great advantages such as precise control over size, shape distribution, and high crystallinity that do not require postannealing treatment. Among various SFNs, FeO nanoparticles have attracted tremendous attention because of their favorable physical and structural properties which are advantageous, especially in biomedical applications, among which the vast application of these materials as targeted drug delivery systems, hyperthermia, and imaging agents in cancer therapy can be mentioned. The main focus of this study is to present an introduction to solvothermal method and key synthesis parameters of SFNs through this synthesis route. Moreover, most recent progress on the potential applications of FeO nanoparticles as the most important compound among the spinel ferrites family members is discussed.
目前，溶剂热制备方法已广泛应用于尖晶石铁氧体纳米颗粒（SFNs）的合成，这主要是因为它具有诸多显著优势，如能精确控制尺寸、形状分布，且结晶度高，无需进行退火后处理。在各种SFNs中，FeO纳米颗粒因其良好的物理和结构特性而备受关注，这些特性尤其在生物医学应用中具有优势，其中可提及这些材料作为靶向药物递送系统、热疗和癌症治疗中的成像剂的广泛应用。本研究的主要重点是介绍通过该合成路线的溶剂热法及SFNs的关键合成参数。此外，还讨论了作为尖晶石铁氧体家族成员中最重要化合物的FeO纳米颗粒在潜在应用方面的最新进展。
