Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21491-902, Brazil; These authors share first authorship.
Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21491-902, Brazil.
Trends Plant Sci. 2018 Aug;23(8):731-747. doi: 10.1016/j.tplants.2018.05.005. Epub 2018 Jun 19.
Oscillation in energy levels is widely variable in dividing and differentiated cells. To synchronize cell proliferation and energy fluctuations, cell cycle-related proteins have been implicated in the regulation of mitochondrial energy-generating pathways in yeasts and animals. Plants have chloroplasts and mitochondria, coordinating the cell energy flow. Recent findings suggest an integrated regulation of these organelles and the nuclear cell cycle. Furthermore, reports indicate a set of interactions between the cell cycle and energy metabolism, coordinating the turnover of proteins in plants. Here, we discuss how cell cycle-related proteins directly interact with energy metabolism-related proteins to modulate energy homeostasis and cell cycle progression. We provide interfaces between cell cycle and energy metabolism-related proteins that could be explored to maximize plant yield.
细胞分裂和分化时，其能级波动广泛多变。为了使细胞增殖和能量波动同步，细胞周期相关蛋白已被牵涉到酵母和动物中线粒体产能途径的调控中。植物有叶绿体和线粒体，它们共同协调细胞能量流。最近的研究结果表明，这些细胞器和核细胞周期受到综合调控。此外，有报告指出，细胞周期和能量代谢之间存在一系列相互作用，共同协调植物中蛋白质的周转。在这里，我们讨论了细胞周期相关蛋白如何直接与能量代谢相关蛋白相互作用，以调节能量平衡和细胞周期进程。我们提供了细胞周期和能量代谢相关蛋白之间的接口，这些接口可以被探索以最大化植物产量。
