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系统性红斑狼疮患者的高血压、糖尿病和血脂异常的识别与控制。

Recognition and control of hypertension, diabetes, and dyslipidemia in patients with systemic lupus erythematosus.

机构信息

Hospital das Clínicas e Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Av. Professor Alfredo Balena, 190, Belo Horizonte, Minas Gerais, 30130-100, Brazil.

出版信息

Clin Rheumatol. 2018 Oct;37(10):2693-2698. doi: 10.1007/s10067-018-4169-0. Epub 2018 Jun 12.

Abstract

Systemic lupus erythematosus (SLE) patients have a high risk for cardiovascular events, but few studies have evaluated the recognition and none have evaluated the control of cardiovascular risk factors (RF) in SLE patients. The study aims to describe the recognition and control frequencies of systemic arterial hypertension (SAH), dyslipidemia, and diabetes mellitus (DM) in SLE patients. Of the female patients with SLE, 137 answered a questionnaire focused on general knowledge of the RF for coronary artery disease (CAD) and on recognition of the risk factors that they possess. The patient's information collected on a structured medical record was reviewed to evaluate the RF control. The mean age was 29.1 (9.6) years. Seventy patients had SAH; 85.7% recognized their condition and 71.4% had desirable blood pressure (BP) control (< 140 × 90 mmHg). From a group of 63 patients with dyslipidemia, 68.3% recognized that they had dyslipidemia and 69.8% had desirable LDL-cholesterol (< 130 mg/dL). Sixteen patients had DM; 87.5% admitted being diabetic and 50.0% had desirable glycemic control (HbA1C < 7%). Most patients were aware of presenting SAH, DM, or dyslipidemia, and the recognition frequency was higher in comparison to general population. The SAH and dyslipidemia control frequencies were higher than that described for the general population.

摘要

系统性红斑狼疮(SLE)患者发生心血管事件的风险较高,但很少有研究评估过 SLE 患者对心血管风险因素(RF)的认知情况,更没有研究评估过对这些 RF 的控制情况。本研究旨在描述 SLE 患者中系统性动脉高血压(SAH)、血脂异常和糖尿病(DM)的识别和控制频率。在女性 SLE 患者中,有 137 名患者回答了一份问卷,重点关注冠心病(CAD)RF 的一般知识以及对自身所具有的 RF 的识别。回顾患者的结构化病历信息以评估 RF 控制情况。患者的平均年龄为 29.1(9.6)岁。70 名患者患有 SAH;71.4%的患者知晓自己的病情,71.4%的患者血压(BP)控制理想(<140×90mmHg)。在 63 名血脂异常患者中,有 68.3%的患者知晓自己患有血脂异常,69.8%的患者 LDL-胆固醇控制理想(<130mg/dL)。16 名患者患有 DM;87.5%的患者承认自己患有糖尿病,50.0%的患者血糖控制理想(HbA1C<7%)。大多数患者意识到自己患有 SAH、DM 或血脂异常,且与一般人群相比,这些 RF 的识别率更高。SAH 和血脂异常的控制频率高于一般人群的报道。

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