Department of Otolaryngology and Neurological Surgery, University of Miami Miller School of Medicine, Miami, USA
Department of Gastroenterology, University of Miami Miller School of Medicine, Miami USA
Balkan Med J. 2018 Sep 21;35(5):367-372. doi: 10.4274/balkanmedj.2018.0853. Epub 2018 Jun 28.
The etiology and the underlying pathogenetic mechanisms of autism spectrum disorders are still largely unknown. This article provides a comprehensive review of the studies that are relevant to autism spectrum disorders and central auditory processing disorders and also discusses the relationship between autism spectrum disorders and central auditory processing disorders in the light of recent studies on this subject, which may provide new pathways in a therapeutic perspective. Several studies confirm that most of the individuals with an autism spectrum disorder have some degree of sensory dysfunction related to disorders of processing auditory, visual, vestibular, and/or tactile stimuli. Among these studies, some have addressed central auditory processing disorders. There is an increasing amount of effort for studies regarding the link between autism spectrum disorders and central auditory processing disorders. Most of the studies investigating central auditory processing disorders in patients with autism spectrum disorders have used electrophysiological measurements such as mismatch negativity and P300 event-related potentials. In addition to these, several studies have reported deterioration in speech perception and expression in patients with autism spectrum disorders, which may also be related to central auditory processing disorders in this unique group of individuals.
自闭症谱系障碍的病因和潜在发病机制仍很大程度上未知。本文对与自闭症谱系障碍和中枢听觉处理障碍相关的研究进行了全面综述，并根据该主题的最新研究讨论了自闭症谱系障碍和中枢听觉处理障碍之间的关系，这可能为治疗提供新途径。几项研究证实，大多数自闭症谱系障碍患者都存在与听觉、视觉、前庭和/或触觉刺激处理障碍相关的某种程度的感觉功能障碍。其中一些研究涉及中枢听觉处理障碍。目前，越来越多的研究致力于探索自闭症谱系障碍与中枢听觉处理障碍之间的联系。大多数研究自闭症谱系障碍患者的中枢听觉处理障碍的研究使用了电生理测量，如失匹配负波和 P300 事件相关电位。除此之外，一些研究还报告了自闭症谱系障碍患者的言语感知和表达能力下降，这也可能与这一独特人群的中枢听觉处理障碍有关。
