恶性胸腔积液的治疗
Treatment of malignant pleural effusion.
作者信息
Terra Ricardo Mingarini, Dela Vega Alberto Jorge Monteiro
机构信息
Thoracic Surgery Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil.
Thoracic Surgery Division, Instituto do Câncer do Estado de São Paulo, Universidade de Sao Paulo, São Paulo, SP, Brazil.
出版信息
J Vis Surg. 2018 May 22;4:110. doi: 10.21037/jovs.2018.05.02. eCollection 2018.
Abstract
Malignant pleural effusion (MPE) is a very disabling condition that often affects patients with advanced neoplasm. Conservative approach, repeated thoracentesis, pleurodesis and use of indwelling pleural catheters (IPC) are the main methods to deal with this condition. The ideal treatment must focus on symptom relief and has to take into account patient underlying diseases, performance status and necessity of adequate tissue sample for diagnosis. In a video we show techniques to perform video assisted thoracic surgery (VATS) pleural biopsy and talc poudrage pleurodesis.
摘要
恶性胸腔积液（MPE）是一种极具致残性的病症，常影响晚期肿瘤患者。保守治疗方法、反复胸腔穿刺术、胸膜固定术以及使用留置胸腔导管（IPC）是应对这种病症的主要手段。理想的治疗必须专注于缓解症状，并且必须考虑患者的基础疾病、身体状况以及获取足够组织样本用于诊断的必要性。在一段视频中，我们展示了进行电视辅助胸腔镜手术（VATS）胸膜活检和滑石粉胸膜固定术的技术。
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本文引用的文献
1
What happens to the pleural space affected by malignant effusion after bedside pleurodesis?
J Surg Oncol. 2018 Jun;117(7):1556-1562. doi: 10.1002/jso.25040. Epub 2018 Mar 24.
2
Malignant Pleural Effusion: From Diagnostics to Therapeutics.
Clin Chest Med. 2018 Mar;39(1):181-193. doi: 10.1016/j.ccm.2017.11.004. Epub 2017 Dec 13.
3
Effect of an Indwelling Pleural Catheter vs Talc Pleurodesis on Hospitalization Days in Patients With Malignant Pleural Effusion: The AMPLE Randomized Clinical Trial.
JAMA. 2017 Nov 21;318(19):1903-1912. doi: 10.1001/jama.2017.17426.
4
Ultrasound-guided intrapleural positioning of pleural catheters: influence on immediate lung expansion and pleurodesis in patients with recurrent malignant pleural effusion.
J Bras Pneumol. 2017 May-Jun;43(3):190-194. doi: 10.1590/S1806-37562016000000240.
5
Management of malignant pleural effusion: challenges and solutions.
Cancer Manag Res. 2017 Jun 23;9:229-241. doi: 10.2147/CMAR.S95663. eCollection 2017.
6
Volume-based quantification using dual-energy computed tomography in the differentiation of thymic epithelial tumours: an initial experience.
Eur Radiol. 2017 May;27(5):1992-2001. doi: 10.1007/s00330-016-4542-9. Epub 2016 Aug 23.
7
Interventions for the management of malignant pleural effusions: a network meta-analysis.
Cochrane Database Syst Rev. 2016 May 8;2016(5):CD010529. doi: 10.1002/14651858.CD010529.pub2.
8
Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial.
JAMA. 2015;314(24):2641-53. doi: 10.1001/jama.2015.16840.
9
Safety Profile of the Use of Iodopovidone for Pleurodesis in Patients with Malignant Pleural Effusion.
Respiration. 2015;90(5):369-75. doi: 10.1159/000440727. Epub 2015 Oct 7.
10
Safety and systemic consequences of pleurodesis with three different doses of silver nitrate in patients with malignant pleural effusion.
Respiration. 2015;89(4):276-83. doi: 10.1159/000371470. Epub 2015 Mar 24.
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