Matteucci D J, Organ C H, Dykstra M, Zalasney B, Jenkins H
Dis Colon Rectum. 1985 Sep;28(9):653-7. doi: 10.1007/BF02553442.
Published guidelines from the Center for Disease Control (CDC) "strongly recommended" gas sterilization or 30 minutes of high-level disinfection with either 2 percent glutaraldehyde or 6 percent hydrogen peroxide following each flexible endoscope cleansing for proper care. The guidelines were proposed on the basis of previous CDC studies performed on glutaraldehyde disinfection of respiratory equipment. A prospective study was performed culturing flexible endoscopes following cannulation of the lower gastrointestinal tract and cleansing. A uniform endoscope cleansing method without gas sterilization or high-level disinfection was used between patients. Thirty aerobic and 30 anaerobic RODAC bacterial culturings revealed no obligate anaerobic organism growth and only sparse, aerobic, environmental and cutaneous organism growth. There were no instances of documented or suspected postendoscopy infectious complications. Our results indicate that high-level disinfection and gas sterilization of flexible endoscopes are not necessary to prevent bacterial disease transmission from patient to patient.
美国疾病控制中心（CDC）发布的指南“强烈建议”，每次软性内窥镜清洁后，采用气体灭菌或用2%的戊二醛或6%的过氧化氢进行30分钟的高水平消毒，以确保妥善护理。这些指南是根据疾病预防控制中心先前对呼吸设备进行戊二醛消毒的研究提出的。进行了一项前瞻性研究，对下消化道插管和清洁后的软性内窥镜进行培养。患者之间采用统一的内窥镜清洁方法，不进行气体灭菌或高水平消毒。30次需氧菌和30次厌氧菌RODAC细菌培养显示，没有专性厌氧菌生长，只有少量的需氧菌、环境菌和皮肤菌生长。没有记录在案或疑似的内窥镜检查后感染并发症病例。我们的结果表明，软性内窥镜的高水平消毒和气体灭菌对于预防患者之间的细菌疾病传播并非必要。
