Lee Jee Young, Jeon Yongduk, Ahn Mi Young, Ann Hea Won, Jung In Young, Jung Wooyong, Kim Moo Hyun, Ahn Jin Young, Song Je Eun, Kim Yong Chan, Oh Dong Hyun, Kim Eun Jin, Jeong Su Jin, Ku Nam Su, Kim Hyunsoo, Lee Kyungwon, Kim June Myung, Choi Jun Yong
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Infect Chemother. 2018 Jun;50(2):149-152. doi: 10.3947/ic.2018.50.2.149.
Brucellosis is a zoonotic infection that is usually transmitted from cattle to humans through ingestion of animal milk, direct contact with animal parts, or inhalation of aerosolized particles. In Korea, brucellosis seem to be transmitted through close contact with blood, fetus, urine, and placenta of domestic cow that has been infected by Brucella abortus, or inhalation of B. arbortus while examining or slaughtering cow. Brucella melitensis infection is rare in Korea and there have been no reported cases of B. melitensis originating from other countries until now. This report details a case of complicated brucellosis with infective spondylitis in a 48-year-old male construction worker recently returned from Iraq. Infection with B. melitensis was confirmed using 16s rRNA sequencing and omp31 gene analysis. The patient was successfully treated using a combination of rifampin, doxycycline, and streptomycin, in accordance with WHO guidelines. This is the first reported case of complicated brucellosis with infective spondylitis in Korea caused by B. melitensis originating from Iraq.
布鲁氏菌病是一种人畜共患感染病，通常通过摄入动物奶、直接接触动物身体部位或吸入雾化颗粒从牛传染给人类。在韩国，布鲁氏菌病似乎是通过与感染了流产布鲁氏菌的家牛的血液、胎儿、尿液和胎盘密切接触，或在检查或屠宰牛时吸入流产布鲁氏菌而传播的。马尔他布鲁氏菌感染在韩国较为罕见，迄今为止尚无源自其他国家的马尔他布鲁氏菌病例报告。本报告详细介绍了一名最近从伊拉克返回的48岁男性建筑工人患伴有感染性脊柱炎的复杂性布鲁氏菌病的病例。通过16s rRNA测序和omp31基因分析确诊为马尔他布鲁氏菌感染。根据世界卫生组织的指南，该患者通过利福平、强力霉素和链霉素联合治疗成功治愈。这是韩国首例由源自伊拉克的马尔他布鲁氏菌引起的伴有感染性脊柱炎的复杂性布鲁氏菌病报告病例。
