Center for Translation Research and Implementation Science, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Fogarty International Center, National Institutes of Health, Bethesda, MD, USA.
Glob Heart. 2018 Jun;13(2):131-137. doi: 10.1016/j.gheart.2018.05.001. Epub 2018 Jun 30.
Globally, most of the burden from noncommunicable disease is now evident in low- and middle-income countries (LMICs). At the same time, many effective noncommunicable disease interventions are now available and recommended for implementation and scale-up across LMIC health systems-yet are not being widely implemented. Understanding optimal and sustainable implementation strategies for these interventions within the LMIC context will need locally led and conducted implementation research- a research capacity which currently is lacking. The National Institutes of Health institutes, centers, and offices work with the Fogarty International Center to support biomedical research and research training across the globe. The National Heart, Lung, and Blood Institutes' Center for Translation Research and Implementation Science has a strategic focus on implementation research in global health. The Center for Translation Research and Implementation Science is considering strategies for developing research capacity and skill sets to conduct this priority research along with National Institutes of Health institutes and centers and other key global institutions that highly value implementation research. Short-term and medium-term strategies will be needed along with building on current efforts and investments and considering new efforts to address gaps. Developing and sustaining this research workforce will present many challenges and require much effort, but the returns could be transformative in advancing the prevention, treatment, and control of noncommunicable diseases within LMICs.
在全球范围内,大多数非传染性疾病负担现在在中低收入国家(LMICs)中显现出来。与此同时,许多有效的非传染性疾病干预措施现在已经可用,并建议在 LMIC 卫生系统中实施和扩大规模——但尚未得到广泛实施。要了解这些干预措施在 LMIC 背景下的最佳和可持续实施策略,需要由当地主导和开展实施研究——而目前这方面的研究能力还很缺乏。美国国立卫生研究院的研究所、中心和办事处与福格蒂国际中心合作,在全球范围内支持生物医学研究和研究培训。国家心肺血液研究所的转化研究和实施科学中心专注于全球卫生中的实施研究。转化研究和实施科学中心正在考虑制定研究能力和技能的战略,以便与国立卫生研究院的研究所、中心和其他非常重视实施研究的关键全球机构一起开展这一优先研究。需要制定短期和中期战略,同时在利用现有努力和投资的基础上,考虑新的努力来解决差距问题。发展和维持这支研究队伍将面临许多挑战,需要付出巨大努力,但这将对推进中低收入国家非传染性疾病的预防、治疗和控制产生变革性的影响。