Lee Arang, Kim Ye Ji, Oh Seung-Won, Lee Cheol Min, Choi Ho Chun, Joh Hee-Kyung, Oh Bumjo, Hwang Seung-Sik, Kim Seung Jae, Kwon Oh Deog
Department of Family Medicine, Seoul National University College of Medicine, Seoul, Korea.
Department of Family Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea.
Korean J Fam Med. 2018 Jul;39(4):239-246. doi: 10.4082/kjfm.17.0099. Epub 2018 Jul 4.
Cut-off values for visceral fat area (VFA) measured by computed tomography (CT) for identifying individuals at risk of metabolic syndrome (MetS) have not been clearly established in Korean adults, particularly for large populations. We aimed to identify optimal VFA and waist circumference (WC) cut-off values and compare the ability of VFA and WC to predict the presence of ≥2 metabolic risk factors.
We included 36,783 subjects aged 19-79 years undergoing abdominal fat CT during regular health checkups between January 2007 and February 2015 in Seoul. The risk factors for MetS except WC were based on the International Diabetes Federation criteria. Receiver operating characteristic curve analyses were used to determine the appropriate VFA and WC cut-off values for MetS.
VFA was a more significant predictor of metabolic risk factors than WC and body mass index (BMI). The optimal cut-off values for VFA and WC were 134.6 cm2 and 88 cm for men and 91.1 cm2 and 81 cm for women, respectively. We estimated age-specific cut-off values for VFA, WC, and BMI. VFA cut-off values increased with age, particularly among women.
This large population study proposed the cut-off values for VFA and WC for identifying subjects at risk of MetS among Korean adults. For more accurate diagnosis, different age-specific cut-off values for VFA and WC may be considered.
在韩国成年人中，尤其是在大样本人群中，通过计算机断层扫描（CT）测量的内脏脂肪面积（VFA）用于识别代谢综合征（MetS）风险个体的临界值尚未明确确立。我们旨在确定最佳的VFA和腰围（WC）临界值，并比较VFA和WC预测存在≥2种代谢风险因素的能力。
我们纳入了2007年1月至2015年2月在首尔定期健康检查期间接受腹部脂肪CT检查的36,783名19 - 79岁的受试者。除WC外，MetS的风险因素基于国际糖尿病联盟标准。采用受试者工作特征曲线分析来确定MetS的合适VFA和WC临界值。
VFA比WC和体重指数（BMI）更能显著预测代谢风险因素。男性VFA和WC的最佳临界值分别为134.6 cm²和88 cm，女性分别为91.1 cm²和81 cm。我们估计了VFA、WC和BMI的年龄特异性临界值。VFA临界值随年龄增加，尤其是在女性中。
这项大样本人群研究提出了韩国成年人中用于识别MetS风险受试者的VFA和WC临界值。为了更准确的诊断，可以考虑VFA和WC不同的年龄特异性临界值。
