Suppr超能文献

基于次级带电粒子注量谱的剂量转换因子分解:在光子场横向剂量分布中的应用。

Decomposition of the dose conversion factor based on fluence spectra of secondary charged particles: Application to lateral dose profiles in photon fields.

作者信息

Hartmann Günther H, Zink Klemens

机构信息

German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.

Institute of Medical Physics and Radiation Protection (IMPS), University of Applied Sciences Giessen, 35390, Giessen, Germany.

出版信息

Med Phys. 2018 Jul 5. doi: 10.1002/mp.13081.

Abstract

PURPOSE

The dose conversion factor plays an important role in the dosimetry by enabling the absorbed dose in the sensitive volume of a detector to be converted into the absorbed dose in the surrounding medium (in most cases water). The purpose of this paper is to demonstrate that a specific fluence-based approach for the decomposition of the dose conversion factor is in particular useful for the interpretation of the influences of detector properties on measurements under nonreference conditions.

METHODS

Data for the dose conversion factor and secondary fluence spectra were obtained by the Monte Carlo method. The calculation of the secondary charged particle fluence (electrons and positrons) in the sensitive detector volume was imbedded into the code for the calculation of absorbed dose in the detector. The decomposition method into subfactors is based on the use of these fluence data applied to a stepwise transition from the dose at the point of measurement next to a pure water detector and finally to the fully simulated detector geometry. Each subfactor is obtained as a ratio, at which the stopping power only is different in the numerator and the denominator or at which the fluence only is different in the numerator and the denominator. This method was applied at photon dose profiles obtained in water at different radiation qualities and with various detectors of cylindrical type.

RESULTS

The resulting subfactors can be well identified as a stopping power ratio and as perturbation factors each reflecting particular detector properties. Two of them (f1 and f ) are equivalent with perturbation factors which have already been introduced by other authors previously. These are the volume perturbation factor and the extracameral perturbation factor. Subfactor f2 denoted as medium perturbation factor was found to resemble the density perturbation factor. Results obtained for the volume perturbation factor applied to dose profiles measured with cylindrical detectors confirm that the volume effect can be well described by a convolution of the true profile in water with a Gaussian kernel. It was found that the sigma parameter depends on the cylinder radius only and amounts almost exactly to half of its value. The medium perturbation factor strongly depends on the density of the detector medium. For an air-filled detector, the influence of the air again can be described by a Gauss convolution, however, with a less good agreement. For detectors with a density of the cavity medium larger than that of water, for instance, for a diamond detector, it was found that there is a tendency of compensation between the volume averaging effect and the medium effect.

CONCLUSION

The fluence-based decomposition of the dose conversion factor leads to a fluence-based formulation of perturbation factors, referred to as volume, medium, and extracameral perturbation factor. These factors offer useful explanations for the behavior of detectors in nonreference conditions. An example was given for cylindrical detectors at dose profile measurements.

摘要

目的

剂量转换因子在剂量学中起着重要作用,它能使探测器灵敏体积内的吸收剂量转换为周围介质(大多数情况下为水)中的吸收剂量。本文的目的是证明一种基于注量的剂量转换因子分解方法对于解释探测器特性在非参考条件下对测量的影响特别有用。

方法

通过蒙特卡罗方法获得剂量转换因子和次级注量谱的数据。将灵敏探测器体积内次级带电粒子(电子和正电子)注量的计算嵌入到探测器吸收剂量计算代码中。分解为子因子的方法基于使用这些注量数据,应用于从纯水探测器旁测量点的剂量逐步过渡到最终完全模拟的探测器几何形状。每个子因子通过一个比值获得,在该比值中,仅阻止本领在分子和分母中不同,或者仅注量在分子和分母中不同。该方法应用于在不同辐射品质下于水中获得的光子剂量分布以及各种圆柱形探测器。

结果

所得子因子可很好地识别为阻止本领比和扰动因子,每个都反映特定的探测器特性。其中两个(f1和f)与其他作者先前已经引入的扰动因子等效。这些是体积扰动因子和腔外扰动因子。表示为介质扰动因子的子因子f2被发现类似于密度扰动因子。应用于用圆柱形探测器测量的剂量分布的体积扰动因子的结果证实,体积效应可以通过水中真实分布与高斯核的卷积很好地描述。发现西格玛参数仅取决于圆柱半径,几乎恰好等于其值的一半。介质扰动因子强烈取决于探测器介质的密度。对于充气探测器,空气的影响同样可以通过高斯卷积来描述,然而,一致性较差。对于腔介质密度大于水的探测器,例如金刚石探测器,发现体积平均效应和介质效应之间存在补偿趋势。

结论

基于注量的剂量转换因子分解导致基于注量的扰动因子公式化,称为体积、介质和腔外扰动因子。这些因子为探测器在非参考条件下的行为提供了有用的解释。给出了圆柱形探测器在剂量分布测量中的一个例子。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验