Department of Medicine and Health Science "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
Family Pediatrician, National Coordinator, Dermatology Network, Italian Federation of Pediatricians (FIMP), Naples, Italy.
Int J Dermatol. 2018 Nov;57(11):1320-1323. doi: 10.1111/ijd.14138. Epub 2018 Jul 5.
Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous follicles that affects patients of all ages with a younger onset being more common than in the past.
To investigate on the prevalence, clinical features and treatments of acne in 9 to 14-year-old patients.
A prospective observational study was conducted between April 2016 and May 2016. The study population consisted of patients attending 32 different pediatric ambulatory clinics located in Italy (North: 56.25%, Center: 18.75%, South: 25%). For each patient, a specific questionnaire was registered: i) demographic data; ii) past personal history of acne; iii) auxologic parameters. Further data were gathered for patients suffering from acne at study enrollment: i) body areas involved by the disease; ii) acne severity evaluated through a 0-5 scale (Global Evaluation Acne scale); iii) acne treatments.
A total of 683 children (49.2% male; mean age 11.05 ± 1.4 years) were enrolled. Acne was present in 234/683 (34.3%) of the patients, and its prevalence increased with age being higher after 13 years of age (85/234; 36.3%) and lowest at 9 years of age (14/234; 6%). The majority of the patients suffering from acne showed a mild or almost clear disease state severity (GEA scale 1 or 2) (207/234, 88.5%), whereas severe or very severe forms (GEA scale 4 or 5) represented only 4/234, 1.7% of the cases.
Acne is not a rare disease in pre-adolescent age. Adequate and prompt treatment is also needed in this class of patient to minimize disease burden and potential future disease worsening.
寻常痤疮是一种累及毛囊皮脂腺的慢性炎症性疾病，可影响各年龄段的患者，其发病年龄较以往更早。
调查 9 至 14 岁患者痤疮的患病率、临床特征和治疗方法。
本研究为前瞻性观察性研究，于 2016 年 4 月至 5 月期间在意大利 32 家不同儿科门诊进行。研究人群包括就诊于意大利北部（56.25%）、中部（18.75%）和南部（25%）32 家不同儿科门诊的患者。每位患者均登记了特定的问卷：i）人口统计学数据；ii）痤疮既往个人史；iii）生长参数。对研究入组时患有痤疮的患者还收集了进一步的数据：i）疾病累及的身体部位；ii）通过 0-5 级评分（全球痤疮评价量表）评估的痤疮严重程度；iii）痤疮治疗方法。
共纳入 683 名儿童（男 49.2%；平均年龄 11.05 ± 1.4 岁）。234/683（34.3%）名患者患有痤疮，且患病率随年龄增长而增加，13 岁后更高（85/234；36.3%），9 岁时最低（14/234；6%）。大多数患有痤疮的患者疾病严重程度为轻度或几乎无疾病（GEA 评分 1 或 2）（207/234，88.5%），而严重或非常严重（GEA 评分 4 或 5）的仅占 4/234，占病例的 1.7%。
在青春期前痤疮并不少见。在该年龄段的患者中也需要进行充分和及时的治疗，以尽量减轻疾病负担并防止未来疾病恶化。
