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拉丁美洲和伊比利亚半岛成人痤疮的大型前瞻性研究:危险因素、人口统计学和临床特征。

Large prospective study on adult acne in Latin America and the Iberian Peninsula: risk factors, demographics, and clinical characteristics.

机构信息

Department of Dermatology, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.

Director of Medical Education, Department of Dermatology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.

出版信息

Int J Dermatol. 2019 Nov;58(11):1277-1282. doi: 10.1111/ijd.14441. Epub 2019 Mar 18.

Abstract

BACKGROUND

Acne vulgaris is a chronic, multifactorial inflammatory skin disease involving the pilosebaceous unit. The prevalence of acne is high during adolescence and is known to persist into adulthood; however, the characteristics of adult acne have not been well established. In the adult population, acne has been associated with psychosocial repercussions impacting the quality of life of those who suffer it, especially in female patients.

METHODS

This study assessed the demographic and clinical characteristics of 1,384 patients between the ages of 25 and 60 years from 21 countries in Latin America and the Iberian Peninsula, with the purpose of identifying parameters for the severity of the disease, its links to demographic, biological, social, and environmental factors, and potential triggers.

RESULTS

Gender differences in severity and location of the lesions were identified. In a univariate analysis, the male gender, use of cosmetics, age of onset of adolescence, and signs of hyperandrogenism were associated with acne severity.

CONCLUSIONS

The characteristics of adult acne may vary from those of adolescent acne, although the disease presentations are generally similar. Further research is needed to establish similarities and differences in manifestations of adult acne versus adolescent acne.

摘要

背景

寻常痤疮是一种累及毛囊皮脂腺单位的慢性、多因素炎症性皮肤病。痤疮的患病率在青春期很高,已知会持续到成年期;然而,成人痤疮的特征尚未得到很好的确定。在成年人群中,痤疮与影响患者生活质量的心理社会影响有关,尤其是在女性患者中。

方法

本研究评估了来自拉丁美洲和伊比利亚半岛 21 个国家的年龄在 25 至 60 岁之间的 1384 名患者的人口统计学和临床特征,目的是确定疾病严重程度的参数、其与人口统计学、生物学、社会和环境因素以及潜在诱因的关系。

结果

发现了严重程度和病变位置的性别差异。在单因素分析中,男性、使用化妆品、青春期发病年龄和高雄激素血症的迹象与痤疮严重程度相关。

结论

成人痤疮的特征可能与青少年痤疮不同,尽管疾病表现通常相似。需要进一步研究以确定成人痤疮与青少年痤疮的表现相似性和差异性。

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