儿童肿瘤学组放射肿瘤学科：15 年来为儿童癌症治疗做出的贡献。
The Children's Oncology Group Radiation Oncology Discipline: 15 Years of Contributions to the Treatment of Childhood Cancer.
机构信息
Department of Radiation Oncology, University of Cincinnati, Cincinnati, Ohio.
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
出版信息
Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):860-874. doi: 10.1016/j.ijrobp.2018.03.002. Epub 2018 Mar 14.
Abstract
PURPOSE
Our aim was to review the advances in radiation therapy for the management of pediatric cancers made by the Children's Oncology Group (COG) radiation oncology discipline since its inception in 2000.
METHODS AND MATERIALS
The various radiation oncology disease site leaders reviewed the contributions and advances in pediatric oncology made through the work of the COG. They have presented outcomes of relevant studies and summarized current treatment policies developed by consensus from experts in the field.
RESULTS
The indications and techniques for pediatric radiation therapy have evolved considerably over the years for virtually all pediatric tumor types, resulting in improved cure rates together with the potential for decreased treatment-related morbidity and mortality.
CONCLUSIONS
The COG radiation oncology discipline has made significant contributions toward the treatment of childhood cancer. Our discipline is committed to continuing research to refine and modernize the use of radiation therapy in current and future protocols with the goal of further improving the cure rates and quality of life of children with cancer.
摘要
目的
本研究旨在回顾 2000 年成立以来，儿童肿瘤学组（COG）放射肿瘤学专业在儿童癌症放射治疗方面的进展。
方法和材料
各放射肿瘤学疾病部位负责人回顾了 COG 开展的工作对儿科肿瘤学的贡献和进展。他们展示了相关研究的结果，并总结了该领域专家通过共识制定的当前治疗政策。
结果
多年来，几乎所有儿科肿瘤类型的放射治疗适应证和技术都有了相当大的发展，这使得治愈率提高，同时降低了与治疗相关的发病率和死亡率。
结论
COG 放射肿瘤学专业为儿童癌症的治疗做出了重大贡献。我们的学科致力于继续研究，以完善和现代化当前和未来方案中放射治疗的使用，目标是进一步提高癌症患儿的治愈率和生活质量。
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