• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿童肿瘤学组放射肿瘤学科:15 年来为儿童癌症治疗做出的贡献。

The Children's Oncology Group Radiation Oncology Discipline: 15 Years of Contributions to the Treatment of Childhood Cancer.

机构信息

Department of Radiation Oncology, University of Cincinnati, Cincinnati, Ohio.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.

出版信息

Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):860-874. doi: 10.1016/j.ijrobp.2018.03.002. Epub 2018 Mar 14.

DOI:10.1016/j.ijrobp.2018.03.002
PMID:29976498
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6548440/
Abstract

PURPOSE

Our aim was to review the advances in radiation therapy for the management of pediatric cancers made by the Children's Oncology Group (COG) radiation oncology discipline since its inception in 2000.

METHODS AND MATERIALS

The various radiation oncology disease site leaders reviewed the contributions and advances in pediatric oncology made through the work of the COG. They have presented outcomes of relevant studies and summarized current treatment policies developed by consensus from experts in the field.

RESULTS

The indications and techniques for pediatric radiation therapy have evolved considerably over the years for virtually all pediatric tumor types, resulting in improved cure rates together with the potential for decreased treatment-related morbidity and mortality.

CONCLUSIONS

The COG radiation oncology discipline has made significant contributions toward the treatment of childhood cancer. Our discipline is committed to continuing research to refine and modernize the use of radiation therapy in current and future protocols with the goal of further improving the cure rates and quality of life of children with cancer.

摘要

目的

本研究旨在回顾 2000 年成立以来,儿童肿瘤学组(COG)放射肿瘤学专业在儿童癌症放射治疗方面的进展。

方法和材料

各放射肿瘤学疾病部位负责人回顾了 COG 开展的工作对儿科肿瘤学的贡献和进展。他们展示了相关研究的结果,并总结了该领域专家通过共识制定的当前治疗政策。

结果

多年来,几乎所有儿科肿瘤类型的放射治疗适应证和技术都有了相当大的发展,这使得治愈率提高,同时降低了与治疗相关的发病率和死亡率。

结论

COG 放射肿瘤学专业为儿童癌症的治疗做出了重大贡献。我们的学科致力于继续研究,以完善和现代化当前和未来方案中放射治疗的使用,目标是进一步提高癌症患儿的治愈率和生活质量。

相似文献

1
The Children's Oncology Group Radiation Oncology Discipline: 15 Years of Contributions to the Treatment of Childhood Cancer.儿童肿瘤学组放射肿瘤学科:15 年来为儿童癌症治疗做出的贡献。
Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):860-874. doi: 10.1016/j.ijrobp.2018.03.002. Epub 2018 Mar 14.
2
Guide for paediatric radiotherapy procedures.儿科放射治疗规程指南。
Cancer Radiother. 2022 Feb-Apr;26(1-2):356-367. doi: 10.1016/j.canrad.2021.11.018. Epub 2021 Dec 27.
3
Pediatric radiation oncology.儿科放射肿瘤学
Invest Radiol. 1986 May;21(5):429-36. doi: 10.1097/00004424-198605000-00016.
4
Can particle beam therapy be improved using helium ions? - a planning study focusing on pediatric patients.能否使用氦离子改善粒子束治疗?——一项针对儿科患者的计划研究。
Acta Oncol. 2016 Jun;55(6):751-9. doi: 10.3109/0284186X.2015.1125016. Epub 2016 Jan 11.
5
Favorable outcomes after whole abdominopelvic radiation therapy for pediatric and young adult sarcoma.小儿和青年肉瘤患者全腹盆腔放射治疗后的良好结局。
Pediatr Blood Cancer. 2014 Sep;61(9):1565-9. doi: 10.1002/pbc.25088. Epub 2014 May 4.
6
Advances in radiotherapy technology for pediatric cancer patients and roles of medical physicists: COG and SIOP Europe perspectives.儿科癌症患者放射治疗技术的进展和医学物理学家的作用:COG 和 SIOP 欧洲观点。
Pediatr Blood Cancer. 2021 May;68 Suppl 2(Suppl 2):e28344. doi: 10.1002/pbc.28344.
7
[Radiotherapy in childhood].[儿童放射治疗]
Z Arztl Fortbild (Jena). 1968 May 15;62(10):521-8.
8
"Per protocol" practice patterns for Children's Oncology Group trials within the radiation oncology community.“按方案”实施儿童肿瘤学组试验的实践模式在放射肿瘤学界内。
Pediatr Blood Cancer. 2023 Aug;70(8):e29673. doi: 10.1002/pbc.29673. Epub 2022 Apr 4.
9
An open invitation to join the Pediatric Proton/Photon Consortium Registry to standardize data collection in pediatric radiation oncology.诚邀加入儿科质子/光子联盟注册中心,以规范儿科放射肿瘤学的数据收集。
Br J Radiol. 2020 Mar;93(1107):20190673. doi: 10.1259/bjr.20190673. Epub 2019 Nov 1.
10
Practice patterns and recommendations for pediatric image-guided radiotherapy: A Children's Oncology Group report.儿科图像引导放疗的实践模式和建议:儿童肿瘤学组报告。
Pediatr Blood Cancer. 2020 Oct;67(10):e28629. doi: 10.1002/pbc.28629. Epub 2020 Aug 9.

引用本文的文献

1
Racial/ethnic disparities in all-cause and cause-specific death among children with malignant central nervous system tumours: a registry-based cohort retrospective analysis.恶性中枢神经系统肿瘤患儿全因死亡和特定病因死亡的种族/民族差异:基于登记处的队列回顾性分析。
EClinicalMedicine. 2024 Sep 5;76:102816. doi: 10.1016/j.eclinm.2024.102816. eCollection 2024 Oct.
2
Ovarian function in female survivors of high-risk neuroblastoma.高危神经母细胞瘤女性幸存者的卵巢功能。
Pediatr Blood Cancer. 2024 Sep;71(9):e31181. doi: 10.1002/pbc.31181. Epub 2024 Jul 5.
3
The Landscape of Pediatric Radiation Oncology in Nigeria.

本文引用的文献

1
Intensive Multimodality Therapy for Extraocular Retinoblastoma: A Children's Oncology Group Trial (ARET0321).眼外视网膜母细胞瘤的强化多模态治疗:儿童肿瘤学组试验(ARET0321)。
J Clin Oncol. 2022 Nov 20;40(33):3839-3847. doi: 10.1200/JCO.21.02337. Epub 2022 Jul 12.
2
Treatment of Childhood Nasopharyngeal Carcinoma With Induction Chemotherapy and Concurrent Chemoradiotherapy: Results of the Children's Oncology Group ARAR0331 Study.儿童鼻咽癌诱导化疗和同期放化疗治疗:儿童肿瘤学组 ARAR0331 研究结果。
J Clin Oncol. 2019 Dec 10;37(35):3369-3376. doi: 10.1200/JCO.19.01276. Epub 2019 Sep 25.
3
Outcome and Prognostic Factors in Stage III Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group Study AREN0532.
尼日利亚儿科放射肿瘤学的现状。
JCO Glob Oncol. 2024 Jan;10:e2300219. doi: 10.1200/GO.23.00219.
4
Large Pelvic Mass in a Female Adolescent: Atypical Presentation and Successful Treatment of Extraskeletal Ewing Sarcoma.一名女性青少年的巨大盆腔肿物:骨外尤文肉瘤的非典型表现及成功治疗
Healthcare (Basel). 2023 May 10;11(10):1373. doi: 10.3390/healthcare11101373.
5
[Application of "kindergarten effect" in radiotherapy for children with tumor aged 3-5 years].["“幼儿园效应”在3 - 5岁肿瘤患儿放疗中的应用"]
Zhongguo Dang Dai Er Ke Za Zhi. 2022 Jun 15;24(6):631-634. doi: 10.7499/j.issn.1008-8830.2202090.
6
Practice Patterns of Pediatric Total Body Irradiation Techniques: A Children's Oncology Group Survey.儿科全身放疗技术的实践模式:儿童肿瘤学组调查。
Int J Radiat Oncol Biol Phys. 2021 Dec 1;111(5):1155-1164. doi: 10.1016/j.ijrobp.2021.07.1715. Epub 2021 Aug 2.
7
Radiation Therapy in the Treatment of Head and Neck Rhabdomyosarcoma.放射治疗在头颈部横纹肌肉瘤治疗中的应用
Cancers (Basel). 2021 Jul 16;13(14):3567. doi: 10.3390/cancers13143567.
8
Childhood Cancer: Occurrence, Treatment and Risk of Second Primary Malignancies.儿童癌症:发病情况、治疗及二次原发性恶性肿瘤风险
Cancers (Basel). 2021 May 26;13(11):2607. doi: 10.3390/cancers13112607.
9
Advances in the management of pediatric genitourinary rhabdomyosarcoma.小儿泌尿生殖系统横纹肌肉瘤的管理进展
Transl Androl Urol. 2020 Oct;9(5):2441-2454. doi: 10.21037/tau-20-480.
10
Preliminary Experience of Treating Children and Young Adults With Image-Guided Proton Beam Therapy in India.印度采用图像引导质子束疗法治疗儿童和青少年的初步经验。
JCO Glob Oncol. 2020 Nov;6:1736-1745. doi: 10.1200/GO.20.00319.
III 期组织学良好型 Wilms 瘤的预后和预后因素:来自儿童肿瘤组研究 AREN0532 的报告。
J Clin Oncol. 2018 Jan 20;36(3):254-261. doi: 10.1200/JCO.2017.73.7999. Epub 2017 Dec 6.
4
Position paper: Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP-RTSG 2016 protocol.立场文件:采用 SIOP-RTSG 2016 方案治疗肾母细胞瘤的理由。
Nat Rev Urol. 2017 Dec;14(12):743-752. doi: 10.1038/nrurol.2017.163. Epub 2017 Oct 31.
5
Results of the First Prospective Multi-institutional Treatment Study in Children With Bilateral Wilms Tumor (AREN0534): A Report From the Children's Oncology Group.双侧肾母细胞瘤患儿的首个前瞻性多机构治疗研究(AREN0534)结果:来自儿童肿瘤协作组的报告
Ann Surg. 2017 Sep;266(3):470-478. doi: 10.1097/SLA.0000000000002356.
6
45 Gy is not sufficient radiotherapy dose for Group III orbital embryonal rhabdomyosarcoma after less than complete response to 12 weeks of ARST0331 chemotherapy: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.对于儿童肿瘤协作组软组织肉瘤委员会报告的III组眼眶胚胎性横纹肌肉瘤,在对ARST0331化疗12周后未达到完全缓解的情况下,45 Gy的放疗剂量并不足够。
Pediatr Blood Cancer. 2017 Sep;64(9). doi: 10.1002/pbc.26540. Epub 2017 May 26.
7
Cancer Statistics, 2017.《2017 年癌症统计》
CA Cancer J Clin. 2017 Jan;67(1):7-30. doi: 10.3322/caac.21387. Epub 2017 Jan 5.
8
Proton therapy - Present and future.质子治疗——现状与未来。
Adv Drug Deliv Rev. 2017 Jan 15;109:26-44. doi: 10.1016/j.addr.2016.11.006. Epub 2016 Dec 3.
9
Predictive Factor Analysis of Response-Adapted Radiation Therapy for Chemotherapy-Sensitive Pediatric Hodgkin Lymphoma: Analysis of the Children's Oncology Group AHOD 0031 Trial.化疗敏感型儿童霍奇金淋巴瘤适应性放疗反应的预测因素分析:儿童肿瘤协作组AHOD 0031试验分析
Int J Radiat Oncol Biol Phys. 2016 Dec 1;96(5):943-950. doi: 10.1016/j.ijrobp.2016.07.015.
10
Late outcomes of adult survivors of childhood non-Hodgkin lymphoma: A report from the St. Jude Lifetime Cohort Study.儿童非霍奇金淋巴瘤成年幸存者的远期结局:圣犹大终身队列研究报告
Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26338. Epub 2016 Nov 15.