Mamo Yosef, Bitew Molalegne, Teklemariam Tsegaye, Soma Murga, Gebre Debebe, Abera Temesgen, Benti Tefera, Deneke Yosef
Jimma University, College of Agriculture and Veterinary Medicine, Jimma, Ethiopia.
Ethiopian Biotechnology Institute, P.O. Box 32853, Addis Ababa, Ethiopia.
Vet Med Int. 2018 May 24;2018:5729296. doi: 10.1155/2018/5729296. eCollection 2018.
Contagious bovine pleuropneumonia (CBPP) is a highly contagious disease of cattle which is one of the great plagues which continues to devastate the cattle herds on which so many people are dependent in Africa. Cross-sectional study was conducted from October 2015 to August 2016 to determine the seroprevalence of CBPP in cattle and associated risk factors in Gimbo district, Southwest Ethiopia. A total of 384 serum samples were collected and tested for the presence of specific antibodies against Mycoplasma mycoides subspecies mycoides small colony (MmmSC), using a competitive enzyme-linked immunosorbent assay (cELISA). Univariable and multivariable logistic regression analysis were performed to determine the association between risk factors and seroprevalence of CBPP. An overall seroprevalence of CBPP was 8.1% (31/384) and it was ranging from 0% to 20% across different Peasant associations (PAs). The seroprevalence of CBPP among adult animals was 8.5% (25) and in young 6.6% (6), in good body condition animals 6.6% (18) and in poor 11.5% (13), in dry season 11.9% (20) and in rainy 5.1% (11), and in highland altitude 2.5% (3), midland 3.8% (5), and lowland 17.4% (23). Among the potential predisposing factors assessed, altitude was found significantly (p = 0.02, OR = 7.3) associated with the seroprevalence of contagious bovine pleuropneumonia and other risk factors had no significant (P > 0.05) influence. The present study showed that the overall seroprevalence of CBPP in Gimbo district was high and this indicates a need for intervening and implementing control measures to prevent further spread of the disease in the district through the use of better and coordinated vaccination program.
牛传染性胸膜肺炎（CBPP）是一种牛的高度传染性疾病，是仍在非洲肆虐牛群的重大瘟疫之一，而许多人的生计依赖这些牛群。于2015年10月至2016年8月开展了一项横断面研究，以确定埃塞俄比亚西南部金博区牛群中牛传染性胸膜肺炎的血清阳性率及相关风险因素。共采集了384份血清样本，并使用竞争酶联免疫吸附测定法（cELISA）检测针对丝状支原体丝状亚种小菌落（MmmSC）的特异性抗体。进行单变量和多变量逻辑回归分析以确定风险因素与牛传染性胸膜肺炎血清阳性率之间的关联。牛传染性胸膜肺炎的总体血清阳性率为8.1%（31/384），在不同农民协会（PA）中范围为0%至20%。成年动物中牛传染性胸膜肺炎的血清阳性率为8.5%（25头），幼畜中为6.6%（6头）；身体状况良好的动物中为6.6%（18头），身体状况差的中为11.5%（13头）；旱季为11.9%（20头），雨季为5.1%（11头）；高海拔地区为2.5%（3头），中部地区为3.8%（5头），低海拔地区为17.4%（23头）。在评估的潜在诱发因素中，发现海拔高度与牛传染性胸膜肺炎血清阳性率显著相关（p = 0.02，OR = 7.3），而其他风险因素无显著影响（P > 0.05）。本研究表明，金博区牛传染性胸膜肺炎的总体血清阳性率较高，这表明需要通过实施更好且协调的疫苗接种计划进行干预并采取控制措施，以防止该疾病在该地区进一步传播。
