Çolakoğlu Ekrem Ç, Börkü Kazım, Haydardedeoğlu Ali E, Alihosseini Hadi, Şenel Oytun O, Yumuşak Nihat, Özen Doğukan, Baş Bülent, Uğurlu Levent
Department of Internal Medicine, Ankara University, 06110 Ankara, Turkey.
Department of Internal Medicine, Faculty of Veterinary Medicine, Aksaray University, 68100 Aksaray, Turkey.
J Vet Res. 2017 Sep 19;61(3):351-355. doi: 10.1515/jvetres-2017-0046. eCollection 2017 Sep.
Chronic gastritis is a common diagnosis in dogs with signs of chronic vomiting. However, there is no data concerning endoscopic and histopathological agreement in dogs with chronic gastritis. Thus, a question should be raised whether taking gastroduodenal biopsies in dogs with chronic gastritis is necessary or not. Consequently, the purpose of the study was to compare the endoscopic and histopathological agreement in dogs with chronic gastritis.
A total of 22 non-pregnant client-owned dogs with the signs of chronic gastritis were enrolled in this prospective study. Procedures including clinical examination, blood analysis, and diagnostic imaging were performed before anaesthesia. Biopsies obtained from gastroduodenal sites were histopathologically evaluated. A total of 110 gastroduodenal samples were examined.
Sixty-eight samples had abnormal histopathology and endoscopy while 11 showed normal histopathological and endoscopic evidence.
The obtained data demonstrated that it is not necessary to take extra gastroduodenal biopsies in dogs with evidence of endoscopic gastroduodenitis. We also believe that further prospective studies, including cost and time effectiveness and more specific comparison between endoscopic appearance and histopathology, are necessary to make final recommendations regarding the need of using both procedures for definitive diagnosis.
慢性胃炎是患有慢性呕吐症状犬类的常见诊断结果。然而,目前尚无关于慢性胃炎犬类内镜检查与组织病理学一致性的数据。因此,一个问题随之而来,即对于患有慢性胃炎的犬类进行胃十二指肠活检是否有必要。所以,本研究的目的是比较慢性胃炎犬类的内镜检查与组织病理学一致性。
本前瞻性研究共纳入22只患有慢性胃炎症状的非妊娠客户自养犬。在麻醉前进行了包括临床检查、血液分析和诊断性成像在内的各项检查。对从胃十二指肠部位获取的活检样本进行组织病理学评估。共检查了110份胃十二指肠样本。
68份样本的组织病理学和内镜检查结果异常,而11份样本的组织病理学和内镜检查结果正常。
所获数据表明,对于有内镜下胃十二指肠炎证据的犬类,无需额外进行胃十二指肠活检。我们还认为,有必要开展进一步的前瞻性研究,包括成本效益和时间效益,以及内镜表现与组织病理学之间更具体的比较,以便就使用这两种检查方法进行确诊的必要性提出最终建议。