Institute of Food Technology, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, H-4032 Debrecen, Hungary.
Food Funct. 2018 Jul 17;9(7):4008-4016. doi: 10.1039/c8fo00064f.
The purpose of this study was to determine whether cherry extract has any effect on salivary α-amylase activity (sAA) or on the level of Streptococcus mutans in human saliva. 70 patients (45 females and 25 males) in three age groups (22 children, 25 young adults, and 23 adults) were examined. All participants completed a questionnaire to obtain information on their oral health behaviour and life style. Clinical examination was performed to record the number of decayed, missing and filled teeth (DMF-T). Saliva samples were collected for the measurement of sAA and the salivary S. mutans level before and after chewing a gum with or without cherry extract. Statistical evaluation of data was performed. S. mutans and the sAA level of unstimulated saliva samples did not depend on either age or gender. The basal sAA value of adult patients was in linear correlation with the dental caries status. Habitual chewing-gum use decreased the resting sAA and the mean of DMF-T. The number of S. mutans cells was significantly lower in the resting saliva of allergic patients. The applied mechanical and gustatory stimuli by chewing gum resulted in higher sAA and S. mutans levels and a slow decrease of values was observed in the control group for the next 30 min. Thereafter, sAA and S. mutans levels decreased earlier in the presence of sour cherry extract than those of control cases. Chewing gum with sour cherry extract may be useful for the prevention of dental caries.
本研究旨在确定樱桃提取物是否对唾液α-淀粉酶活性（sAA）或唾液变形链球菌水平有影响。检查了三个年龄组（22 名儿童、25 名年轻成年人和 23 名成年人）的 70 名患者（45 名女性和 25 名男性）。所有参与者都填写了一份问卷，以获取有关其口腔健康行为和生活方式的信息。进行临床检查以记录龋齿、缺失和补牙的数量（DMF-T）。在咀嚼含有或不含有樱桃提取物的口香糖前后采集唾液样本，用于测量 sAA 和唾液变形链球菌水平。对数据进行了统计评估。唾液变形链球菌和未刺激唾液样本的 sAA 水平既不受年龄也不受性别影响。成年患者的基础 sAA 值与龋齿状况呈线性相关。习惯性咀嚼口香糖可降低静息 sAA 和 DMF-T 的平均值。过敏患者的唾液中变形链球菌的数量明显较低。咀嚼口香糖产生的机械和味觉刺激导致 sAA 和变形链球菌水平升高，在对照组中，接下来的 30 分钟内观察到值的缓慢下降。此后，含有酸樱桃提取物的口香糖中的 sAA 和变形链球菌水平比对照病例更早下降。含酸樱桃提取物的口香糖可能有助于预防龋齿。
