Inhibition of PI3K/AKT/mTOR pathway for the treatment of endometriosis.
作者信息
Barra Fabio, Ferro Desideri Lorenzo, Ferrero Simone
机构信息
Academic Unit of Obstetrics and Gynecology, Ospedale Policlinico San Martino, Genoa, Italy.
Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Genoa, Italy.
出版信息
Br J Pharmacol. 2018 Sep;175(17):3626-3627. doi: 10.1111/bph.14391. Epub 2018 Jul 8.
Abstract
摘要
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Nat Rev Clin Oncol. 2018 May;15(5):273-291. doi: 10.1038/nrclinonc.2018.28. Epub 2018 Mar 6.
2
In vitro and in vivo effects of MK2206 and chloroquine combination therapy on endometriosis: autophagy may be required for regrowth of endometriosis.MK2206 与氯喹联合治疗对子宫内膜异位症的体内外作用：自噬可能是子宫内膜异位症复发所必需的。
Br J Pharmacol. 2018 May;175(10):1637-1653. doi: 10.1111/bph.14170. Epub 2018 Apr 16.
3
Everolimus as an mTOR Inhibitor Suppresses Endometriotic Implants: an Experimental Rat Study.依维莫司作为一种mTOR抑制剂可抑制子宫内膜异位症植入物：一项大鼠实验研究。
Geburtshilfe Frauenheilkd. 2017 Jan;77(1):66-72. doi: 10.1055/s-0042-115566.
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Therapy and pharmacological properties of hydroxychloroquine and chloroquine in treatment of systemic lupus erythematosus, rheumatoid arthritis and related diseases.羟氯喹和氯喹在治疗系统性红斑狼疮、类风湿关节炎及相关疾病中的治疗和药理学特性。
Inflammopharmacology. 2015 Oct;23(5):231-69. doi: 10.1007/s10787-015-0239-y. Epub 2015 Aug 6.
5
Influence of AKT on progesterone action in endometrial diseases.AKT对子宫内膜疾病中孕酮作用的影响。
Biol Reprod. 2014 Sep;91(3):63. doi: 10.1095/biolreprod.114.119255. Epub 2014 Aug 6.
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