College of Chemistry and Chemical Engineering, Henan Key Laboratory of Function-Oriented Porous Materials , Luoyang Normal University , Luoyang 471934 , PR China.
Departments of Physiology and Developmental Biology , University of Texas, Southwestern Medical Center , Dallas , Texas 75390-9133 , United States.
Inorg Chem. 2018 Aug 6;57(15):8866-8873. doi: 10.1021/acs.inorgchem.8b00788. Epub 2018 Jul 9.
A novel optical nanoprobe based on silicon quantum dots (SiQDs) has been assembled through a one-pot low-temperature (40 °C) treatment by using 3-(aminopropyl)trimethoxysilane (APTMS) and ascorbic acid (AA) as two precursors. The water-soluble SiQDs demonstrate intense green luminescence in aqueous environment and the excitation-dependent feature has been explored. Meanwhile, the incorporation of salicylaldehyde (SA) serves to suppress the emission of SiQDs effectively via nucleophilic reaction and an "on-off" change is observed. Furthermore, the addition of Zn can lead to evolution of emission peaks, and the green band at 500 nm gradually shifts toward the blue side at 455 nm. The corresponding ratiometric signal changes ( I/ I) can accurately determine the Zn concentration and the limit of detection is calculated to be 0.17 μM in the linear range between 1 and 100 μM. In this research, a molecular logic gate (AND) system has been well established by using SA and Zn as two inputs. The fluorescence emission changes based on SiQDs will shed new light on the development of functional sensors at the nanoscale level.
一种基于硅量子点（SiQDs）的新型光学纳米探针通过使用 3-（氨丙基）三甲氧基硅烷（APTMS）和抗坏血酸（AA）作为两种前体的一锅低温（40°C）处理组装而成。水溶性 SiQDs 在水相环境中表现出强烈的绿色发光，并且已经探索了激发依赖性特征。同时，通过亲核反应，水杨醛（SA）的掺入有效地抑制了 SiQDs 的发射，并观察到“开-关”变化。此外，添加 Zn 可以导致发射峰的演变，并且在 500nm 处的绿色带逐渐向 455nm 的蓝色侧移动。相应的相对信号变化（I/ I）可以准确地确定 Zn 浓度，并且在线性范围为 1 至 100 μM 之间，检测限计算为 0.17 μM。在这项研究中，使用 SA 和 Zn 作为两个输入，成功建立了分子逻辑门（AND）系统。基于 SiQDs 的荧光发射变化将为纳米尺度功能传感器的发展带来新的曙光。
