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外倒转术尝试与围产儿发病率和死亡率的关系。

Association Between Attempted External Cephalic Version and Perinatal Morbidity and Mortality.

机构信息

Division of Maternal-Fetal Medicine and the Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.

出版信息

Obstet Gynecol. 2018 Aug;132(2):365-370. doi: 10.1097/AOG.0000000000002699.

Abstract

OBJECTIVE

To examine whether, with fetal malpresentation at term, perinatal morbidity and mortality differ between women who undergo an external cephalic version (ECV) attempt and those who do not and are expectantly managed.

METHODS

We conducted a retrospective cohort study of women with nonanomalous singleton gestations in nonvertex presentation delivering at a tertiary care institution from 2006 to 2016. Women undergoing an ECV attempt at 37 weeks of gestation or greater were compared with those with nonvertex fetuses who did not undergo an ECV attempt and delivered at 37 weeks of gestation or greater. The primary outcome was a composite of perinatal morbidity and mortality including stillbirth, neonatal death within 72 hours, Apgar score less than 5 at 5 minutes, umbilical artery pH less than 7.0, base deficit 12 mmol/L or greater, or neonatal therapeutic hypothermia. Secondary outcomes were neonatal intensive care unit admission and neonatal anemia (hemoglobin value less than 13.5 g/dL). Bivariable and multivariable analyses were performed.

RESULTS

Of the 4,117 women meeting eligibility criteria, 1,263 (30.7%) attempted ECV; 509 (40.3%) of these attempts resulted in successful versions. In bivariable analyses, women who underwent attempted ECV were more likely to be non-Hispanic white and multiparous and had lower mean body mass indexes. The composite perinatal morbidity and mortality outcome did not differ significantly between women who did and did not undergo attempted ECV (2.9% vs 2.5%, P=.46). The frequencies of neonatal intensive care unit admission (3.6% vs 3.3%, P=.53) and neonatal anemia (1.6% vs 1.2%, P=.36) were also similar. There continued to be no association between ECV attempt and composite perinatal morbidity and mortality outcome after adjustment for potential confounders (adjusted odds ratio 1.02, 95% CI 0.66-1.60).

CONCLUSION

Compared with expectant management, an ECV attempt at term is not associated with increased perinatal morbidity or mortality.

摘要

目的

研究在足月时胎儿胎位不正的情况下,行外倒转术(ECV)尝试的孕妇与未行 ECV 尝试而期待管理的孕妇之间,围产儿发病率和死亡率是否存在差异。

方法

我们对 2006 年至 2016 年在一家三级医疗机构分娩的非畸形单胎妊娠、非头位的孕妇进行了回顾性队列研究。将妊娠 37 周或以上行 ECV 尝试的孕妇与妊娠 37 周或以上、未行 ECV 尝试而分娩的非头位胎儿孕妇进行比较。主要结局是包括死胎、72 小时内新生儿死亡、5 分钟时 Apgar 评分<5 分、脐动脉 pH 值<7.0、碱剩余 12mmol/L 或更大、新生儿治疗性低温在内的围产儿发病率和死亡率的复合结局。次要结局是新生儿重症监护病房(NICU)入院和新生儿贫血(血红蛋白值<13.5g/dL)。进行了单变量和多变量分析。

结果

在符合纳入标准的 4117 名孕妇中,1263 名(30.7%)尝试了 ECV;509 名(40.3%)尝试获得了成功的胎位转位。在单变量分析中,行 ECV 尝试的孕妇更可能是非西班牙裔白人、多胎产,且平均体重指数较低。在尝试 ECV 尝试的孕妇与未尝试 ECV 尝试的孕妇之间,复合围产儿发病率和死亡率结局没有显著差异(2.9%比 2.5%,P=.46)。NICU 入院率(3.6%比 3.3%,P=.53)和新生儿贫血发生率(1.6%比 1.2%,P=.36)也相似。在校正潜在混杂因素后,ECV 尝试与复合围产儿发病率和死亡率结局之间仍无关联(调整后优势比 1.02,95%CI 0.66-1.60)。

结论

与期待管理相比,足月时行 ECV 尝试不会增加围产儿发病率或死亡率。

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