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波兰版重症监护疼痛观察工具(CPOT)用于评估成年气管插管重症监护病房患者疼痛强度的有效性验证:POL-CPOT研究。

Validation of the Polish version of the Critical Care Pain Observation Tool (CPOT) to assess pain intensity in adult, intubated intensive care unit patients: the POL-CPOT study.

作者信息

Kotfis Katarzyna, Zegan-Barańska Małgorzata, Strzelbicka Marta, Safranow Krzysztof, Żukowski Maciej, Ely E Wesley

机构信息

Department of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University, Szczecin, Poland.

Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland.

出版信息

Arch Med Sci. 2018 Jun;14(4):880-889. doi: 10.5114/aoms.2017.69752. Epub 2017 Sep 1.

Abstract

INTRODUCTION

Pain in the critically ill affects nearly 50% of patients. In patients unable to self-report pain, behavioural scales are used. The aim of this study was to validate the Polish version of the Critical Care Pain Observation Tool (CPOT).

MATERIAL AND METHODS

The prospective observational cohort study included patients observed during non-nociceptive and nociceptive procedures, at rest, during the intervention, and 15 min after each intervention. Assessments included self-report by patients and CPOT assessment carried out by two blinded observers.

RESULTS

A total of 71 patients were included in the study (mean age: 66 years), predominantly males (50/71, 70%), mean APACHE II score 26.04 ±10.56. Results showed an excellent inter-rater correlation (ICC) between raters (ICC scores > 0.97). Self-report NRS (numeric rating scale) scores were available from 58/71 patients (82%). Patients' self-reported pain and CPOT showed a very strong correlation (Spearman's > 0.85, < 0.0001). The CPOT has high diagnostic value for detection of presence of patients' self-reported pain (ROC AUC = 0.938 for rater A and 0.951 for rater B, < 0.0001). CPOT score ≥ 2 is an optimal cut-off to detect pain during a nociceptive procedure. A significantly higher mean CPOT score during a nociceptive procedure as compared to a non-nociceptive procedure or at rest was found ( < 0.0001).

CONCLUSIONS

This study shows that the Polish version of the CPOT can be used to assess pain in critically ill patients with no hypnotic, opioid-based analgo-sedation. Polish CPOT scores correlated well with patients' self-reported presence of pain and showed excellent inter-rater reliability. This makes the Polish version of the CPOT a reliable pain assessment tool.

摘要

引言

危重症患者中近50%会出现疼痛。对于无法自我报告疼痛的患者,需使用行为量表。本研究的目的是验证波兰语版的重症监护疼痛观察工具(CPOT)。

材料与方法

这项前瞻性观察队列研究纳入了在非伤害性和伤害性操作期间、休息时、干预期间以及每次干预后15分钟进行观察的患者。评估包括患者的自我报告以及由两名盲法观察者进行的CPOT评估。

结果

共有71名患者纳入研究(平均年龄:66岁),以男性为主(50/71,70%),平均急性生理学与慢性健康状况评分系统II(APACHE II)评分为26.04±10.56。结果显示评估者之间具有出色的组内相关系数(ICC)(ICC评分>0.97)。58/71名患者(82%)提供了自我报告的数字评分量表(NRS)分数。患者的自我报告疼痛与CPOT显示出非常强的相关性(斯皮尔曼相关系数>0.85,P<0.0001)。CPOT对检测患者自我报告疼痛的存在具有较高的诊断价值(评估者A的ROC曲线下面积[AUC] = 0.938,评估者B的AUC = 0.951,P<0.0001)。CPOT评分≥2是检测伤害性操作期间疼痛的最佳截断值。与非伤害性操作或休息时相比,伤害性操作期间的CPOT平均评分显著更高(P<0.0001)。

结论

本研究表明,波兰语版的CPOT可用于评估未使用催眠、基于阿片类药物的镇痛镇静的危重症患者的疼痛。波兰语版CPOT评分与患者自我报告的疼痛存在情况相关性良好,并显示出出色的评估者间信度。这使得波兰语版的CPOT成为一种可靠的疼痛评估工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b8c/6040120/2a8d3b2e7a06/AMS-14-30499-g001.jpg

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