National Innovation Foundation-India, Amrapur, Grambharti Mahudi Road, Gandhinagar 382 650, Gujarat, India.
National Innovation Foundation-India, Amrapur, Grambharti Mahudi Road, Gandhinagar 382 650, Gujarat, India.
J Integr Med. 2018 Sep;16(5):299-311. doi: 10.1016/j.joim.2018.07.002. Epub 2018 Jul 4.
This article explores the most recent evidence-based information on ethnomedicinal, phytochemical and pharmacological understanding of Hygrophila auriculata for the treatment of various diseases and health conditions. Various ethnomedicinal writings suggest the use of the plant or its parts for the treatment of jaundice, oedema, gastrointestinal ailments, diarrhoea, dysentery, urinogenital disorder, gall stones, urinary calculi, kidney stone, leucorrhoea, rheumatism, tuberculosis, anaemia, body pain, constipation, skin disease, and as an aphrodisiac. The plant has been reported to contain flavonoids (apigenin, luteolin, ellagic acid, gallic acid and quercetin), alkaloids (asteracanthine and asteracanthicine), triterpenes (lupeol, lupenone, hentricontane and betulin), sterols (stigmasterol and asterol), minerals, amino acids, fatty acids, aliphatic esters and essential oils. Extracts and bioactive compounds from the plant have been found to possess antimicrobial, anthelmintic, antitermite, nephroprotective, hepatoprotective, central nervous system protective, antitumour, antidiabetic, anticataract, antioxidant, haematopoietic, diuretic, antinociceptive, anti-inflammatory, antipyretic, antimotility, aphrodisiac, neuroprotection, anti-endotoxin and anti-urolithiatic activities. For this paper, we reviewed patents, clinical studies, analytical studies and marketed formulations from the earliest found examples from 1887 to the end of 2017.
本文探讨了有关 Hygrophila auriculata 的最新循证医学文献，包括其在民族医学、植物化学和药理学方面的应用，以治疗各种疾病和健康状况。各种民族医学著作表明，该植物或其部分可用于治疗黄疸、水肿、胃肠道疾病、腹泻、痢疾、尿生殖系统紊乱、胆结石、尿路结石、肾结石、白带、风湿病、肺结核、贫血、身体疼痛、便秘、皮肤病和作为壮阳药。该植物已被报道含有黄酮类化合物（芹菜素、木樨草素、鞣花酸、没食子酸和槲皮素）、生物碱（ Asteracanthine 和 Asteracanthicine）、三萜（羽扇豆醇、羽扇豆酮、廿五烷和白桦脂醇）、甾醇（豆甾醇和麦角甾醇）、矿物质、氨基酸、脂肪酸、脂肪族酯和精油。该植物的提取物和生物活性化合物已被发现具有抗菌、驱虫、抗白蚁、肾保护、肝保护、中枢神经系统保护、抗肿瘤、抗糖尿病、抗白内障、抗氧化、造血、利尿、镇痛、抗炎、退热、抗蠕动、壮阳、神经保护、抗内毒素和抗尿石形成活性。本文综述了从 1887 年到 2017 年底最早发现的专利、临床研究、分析研究和市售制剂。
