杏仁核损伤消除了恒河猴对人脸的观看偏好。
Amygdala lesions eliminate viewing preferences for faces in rhesus monkeys.
机构信息
Section on Neurocircuitry, Laboratory of Brain and Cognition, The National Institute of Mental Health, Bethesda, MD 20892;
Section on Neurocircuitry, Laboratory of Brain and Cognition, The National Institute of Mental Health, Bethesda, MD 20892.
出版信息
Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):8043-8048. doi: 10.1073/pnas.1807245115. Epub 2018 Jul 16.
In free-viewing experiments, primates orient preferentially toward faces and face-like stimuli. To investigate the neural basis of this behavior, we measured the spontaneous viewing preferences of monkeys with selective bilateral amygdala lesions. The results revealed that when faces and nonface objects were presented simultaneously, monkeys with amygdala lesions had no viewing preference for either conspecific faces or illusory facial features in everyday objects. Instead of directing eye movements toward socially relevant features in natural images, we found that, after amygdala loss, monkeys are biased toward features with increased low-level salience. We conclude that the amygdala has a role in our earliest specialized response to faces, a behavior thought to be a precursor for efficient social communication and essential for the development of face-selective cortex.
在自由观看实验中，灵长类动物更喜欢观看人脸和类人脸刺激。为了研究这种行为的神经基础，我们测量了选择性双侧杏仁核损伤猴子的自发观看偏好。结果表明，当同时呈现人脸和非人脸物体时，杏仁核损伤的猴子对同种动物的脸或日常物体中的虚幻面部特征没有观看偏好。我们发现，猴子的眼动并没有指向自然图像中的社交相关特征，而是偏向于具有更高低水平显著性的特征。相反，我们发现，在杏仁核丧失后，而不是引导眼睛运动朝向自然图像中的社交相关特征，猴子会偏向于具有增加的低水平显著性的特征。我们得出结论，杏仁核在我们对人脸的最早专门反应中起作用，这种行为被认为是有效社交沟通的前体，对于脸选择性皮层的发展至关重要。
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