Hidanah Sri, Sabdoningrum Emy Koestanti, Wahjuni Retno Sri, Chusniati Sri
Department of Animal Husbandry, Jl. Mulyorejo, Kampus C Unair, Surabaya, Indonesia, 60115.
Department of Basic Veterinary Medicine, Jl. Mulyorejo, Kampus C Unair, Surabaya, Indonesia, 60115.
Vet World. 2018 Jun;11(6):834-839. doi: 10.14202/vetworld.2018.834-839. Epub 2018 Jun 22.
This study aimed to evaluate the effects of Meniran extract ( L.) administration on leukocyte profile of broiler chickens infected with .
Thirty broiler chickens, 21 days old were divided into five treatment groups. P0 (-): Chickens without any treatment; P0 (+), P1, P2, and P3: Chickens were infected with 10 cells/ml/animal orally, then given no treatment, Meniran extract 60%, 62.5%, and 65% orally at a dose of 1 ml/kg body weight, respectively. The treatment of Meniran extract was given for 7 days.
Leukocyte count with the lowest number showed in Group P0 (-) and Group P3 (p>0.05). Increased number of basophils was found in Group P0 (+), Group P1, and Group P2. The highest number of heterophils was found in Group P0 (+) and was significantly different from Group P0 to P3 (p<0.05). The same pattern was also seen in the number of lymphocytes in all treatment groups. The number of monocytes showed no significant difference between all treatment groups (p>0.05).
Increased the number of leukocytes is often observed in inflammation due to general infections, trauma, or toxicity. Shifting in the number of heterophile or lymphocytes, an increase in the number of monocytes, basophils, and eosinophils may also be associated with various infectious or inflammatory conditions. Heterophils play a role as an antibacterial defense through several effective mechanisms. When infections and inflammation occur, the heterophils will increase to phagocytosis microbe.
It can be concluded that Meniran extract ( L.) at a dose of 65% can decrease the total number of leukocytes in broilers infected with .
本研究旨在评估施用梅尼兰提取物（L.）对感染……的肉鸡白细胞谱的影响。
将30只21日龄的肉鸡分为五个处理组。P0（-）：未进行任何处理的鸡；P0（+）、P1、P2和P3：鸡口服感染10个细胞/毫升/动物，然后分别不进行处理、口服60%、62.5%和65%的梅尼兰提取物，剂量为1毫升/千克体重。梅尼兰提取物处理7天。
白细胞计数最低的是P0（-）组和P3组（p>0.05）。P0（+）组、P1组和P2组发现嗜碱性粒细胞数量增加。P0（+）组嗜异性粒细胞数量最高，且与P0组至P3组有显著差异（p<0.05）。所有处理组淋巴细胞数量也呈现相同模式。单核细胞数量在所有处理组之间无显著差异（p>0.05）。
由于全身感染、创伤或毒性导致的炎症中，白细胞数量增加很常见。嗜异性粒细胞或淋巴细胞数量的变化、单核细胞、嗜碱性粒细胞和嗜酸性粒细胞数量的增加也可能与各种感染或炎症状况有关。嗜异性粒细胞通过几种有效机制发挥抗菌防御作用。当感染和炎症发生时，嗜异性粒细胞会增加以吞噬微生物。
可以得出结论，65%剂量的梅尼兰提取物（L.）可降低感染……的肉鸡白细胞总数。
