Department of Health Behavior , Roswell Park Comprehensive Cancer Center , Elm and Carlton Streets , Buffalo , New York 14203 , United State.
Chem Res Toxicol. 2018 Aug 20;31(8):643-645. doi: 10.1021/acs.chemrestox.8b00160. Epub 2018 Aug 6.
Marijuana is seeing increased use both globally and domestically. However, the scientific community has not fully reached a consensus about what negative health effects and to what extent marijuana smoking may cause. In this study, we evaluated the associations between the body burdens of polycyclic aromatic hydrocarbons (PAHs) among marijuana smokers and the smoking heaviness. We observed clear, increasing trends of PAH body burdens as marijuana smoking increased. The findings highlight the importance of capturing the heaviness of marijuana smoking in future studies and support the need for well-designed toxicological and epidemiological studies for understanding the health effects of marijuana use in a changing environment.
大麻在全球和国内的使用都有所增加。然而，科学界尚未就大麻吸烟可能导致哪些负面健康影响以及在何种程度上产生影响达成完全共识。在这项研究中，我们评估了大麻吸烟者体内多环芳烃 (PAH) 的负担与吸烟量之间的关联。我们观察到，随着大麻吸烟量的增加，PAH 体内负担呈现出明显的、递增的趋势。这些发现强调了在未来研究中捕捉大麻吸烟量的重要性，并支持进行精心设计的毒理学和流行病学研究，以了解在不断变化的环境中使用大麻的健康影响。
