Sørensen B, Falk E S, Wisløff-Nilsen E, Bjorvatn B, Kristiansen B E
J Gen Microbiol. 1985 Nov;131(11):3099-104. doi: 10.1099/00221287-131-11-3099.
Chromosomal DNA was extracted from eleven Neisseria meningitidis and seven Neisseria gonorrhoeae isolates and cleaved with the restriction enzyme HindIII. The DNA fragments were separated according to their size, using a 4% polyacrylamide gel. The band patterns obtained were digitized and statistically analysed by the SIMCA method. To develop the models for N. meningitidis (class 1) and N. gonorrhoeae (class 2), all eleven meningococci and seven gonococci, were used. All strains were classified correctly and showed an extremely good class separation.
从11株脑膜炎奈瑟菌和7株淋病奈瑟菌分离株中提取染色体DNA，并用限制性内切酶HindIII进行切割。使用4%的聚丙烯酰胺凝胶，根据DNA片段的大小对其进行分离。获得的条带模式进行数字化处理，并通过SIMCA方法进行统计分析。为了建立脑膜炎奈瑟菌（1类）和淋病奈瑟菌（2类）的模型，使用了所有11株脑膜炎球菌和7株淋球菌。所有菌株均被正确分类，并且显示出极好的类别区分。
