Waldvogel A S, Stott J L, Squire K R, Osburn B I
J Gen Virol. 1986 Apr;67 ( Pt 4):765-9. doi: 10.1099/0022-1317-67-4-765.
Two strains of bluetongue virus (BTV) serotype 11, UC-2 and UC-8, were identified by the electrophoretic migration pattern of their genomic RNA segments on polyacrylamide gel electrophoresis. Significant differences in virulence of these two viruses could be demonstrated by subcutaneous inoculation of newborn mice. No signs of disease were observed in mice infected with UC-2. Mice infected with UC-8 died of a severe necrotizing encephalitis, which resembled lesions in bovine and ovine foetuses infected with BTV.
通过蓝舌病病毒11型（BTV-11）的两个毒株UC-2和UC-8的基因组RNA片段在聚丙烯酰胺凝胶电泳上的电泳迁移模式，对它们进行了鉴定。通过对新生小鼠进行皮下接种，可以证明这两种病毒在毒力上存在显著差异。感染UC-2的小鼠未观察到疾病迹象。感染UC-8的小鼠死于严重的坏死性脑炎，这类似于感染蓝舌病病毒的牛和羊胎儿的病变。
