Department of Food Science and Biotechnology, Sungkyunkwan University (SKKU), 2066 Seobu-ro, Jangan-gu, Suwon, 16419, Republic of Korea.
Department of Biotechnology and Bioengineering, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju, 61186, Republic of Korea.
Planta. 2019 Jan;249(1):181-193. doi: 10.1007/s00425-018-2969-8. Epub 2018 Aug 4.
Photosynthetic production of isoprenoids in cyanobacteria is considered in terms of metabolic engineering and biological importance. Metabolic engineering of photosynthetic bacteria (cyanobacteria) has been performed to construct bio-solar cell factories that convert carbon dioxide to various value-added chemicals. Isoprenoids, which are found in nature and range from essential cell components to defensive molecules, have great value in cosmetics, pharmaceutics, and biofuels. In this review, we summarize the recent engineering of cyanobacteria for photosynthetic isoprenoids production as well as carbon molar basis comparisons with heterotrophic isoprenoids production in engineered Escherichia coli.
从代谢工程和生物学重要性两方面考虑蓝藻的类异戊二烯的光合作用生产。已经对光合细菌（蓝藻）进行了代谢工程改造，以构建将二氧化碳转化为各种高附加值化学品的生物太阳能细胞工厂。类异戊二烯在自然界中广泛存在，从必需的细胞成分到防御分子，在化妆品、制药和生物燃料方面具有巨大的价值。在这篇综述中，我们总结了蓝藻光合作用生产类异戊二烯的最新工程进展，并与工程大肠杆菌中异养生产类异戊二烯的碳摩尔基准进行了比较。
