Bridger J C, Pedley S, McCrae M A
J Clin Microbiol. 1986 Apr;23(4):760-3. doi: 10.1128/jcm.23.4.760-763.1986.
Atypical rotaviruses obtained from human feces from Australia, Brazil, and the United Kingdom were shown by a combination of techniques--immunoelectron microscopy, immunofluorescence, genome profile analysis, terminal fingerprint analysis of genome segments, and dot-blot hybridization--to be related to group C porcine rotaviruses. The prevalence of antibody to group C rotaviruses was found to be low in human sera and immunoglobulin pools from six countries. No signs of infection were obtained when one of the human viruses was inoculated into gnotobiotic piglets. We conclude that the atypical human viruses are the first examples of group C rotaviruses in humans.
通过免疫电镜、免疫荧光、基因组图谱分析、基因组片段末端指纹分析和斑点杂交等技术组合显示，从澳大利亚、巴西和英国人类粪便中获得的非典型轮状病毒与C组猪轮状病毒有关。研究发现，来自六个国家的人类血清和免疫球蛋白库中，针对C组轮状病毒的抗体流行率较低。将其中一种人类病毒接种到无菌仔猪体内时，未发现感染迹象。我们得出结论，这些非典型人类病毒是人类中C组轮状病毒的首个实例。
