Hamza Ameer, Zhang Zhifei, Al-Khafaji Basim
St. John Hospital and Medical Center, Department of Pathology. Detroit, MI, United States of America.
Autops Case Rep. 2018 Jul 30;8(3):e2018036. doi: 10.4322/acr.2018.036. eCollection 2018 Jul-Sep.
Sinus histiocytosis with massive lymphadenopathy, generally known by the name of Rosai-Dorfman disease is a rare benign condition principally affecting cervical lymph nodes. Concurrent extra-nodal disease frequently occurs, however, solitary extra-nodal disease involving the mandible is exceedingly rare with less than five reported cases in the English literature. We describe a case of primary involvement of the mandible in a 27-year-old female, and discuss the differential diagnosis of this disease with other histiocytic lesions.
伴巨大淋巴结病的窦性组织细胞增生症,通常以罗萨伊-多夫曼病之名为人所知,是一种主要累及颈部淋巴结的罕见良性疾病。然而,结外疾病常同时发生,累及下颌骨的孤立性结外疾病极为罕见,英文文献中报道的病例不足5例。我们描述了一名27岁女性下颌骨原发性受累的病例,并讨论了该疾病与其他组织细胞性病变的鉴别诊断。