Bo Myat Su, Cheah Whye Lian, Lwin Soe, Moe Nwe Tin, Win Than Than, Aung Myint
Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia.
Department of Community Medicine and Public Health, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia.
J Nutr Metab. 2018 Jul 4;2018:7027624. doi: 10.1155/2018/7027624. eCollection 2018.
Atherogenic index of plasma (AIP) was found to be one of the strongest markers in predicting the cardiovascular disease (CVD) risk. This study was to determine the AIP and its relationship with other CVD risk factors.
This cross-sectional study was done among 349 staff of a public university in Sarawak. Data were collected using questionnaire, blood sampling, and anthropometric and blood pressure measurement. Data were analyzed using IBM SPSS version 20.
A total of 349 respondents participated with majority females (66.8%), aged 38.5 ± 7.82 years. Nearly 80% of the respondents were overweight and obese, 87.1% with high and very high body fat, and 46.9% with abnormal visceral fat. For AIP category, 8.9% were found to be in intermediate and 16.4% were at high risk. Elevated lipid profile showed that total cholesterol (TC) is 15.5%, low density lipoprotein (LDL) is 16.1%, and triglyceride (TG) is 10.6%. AIP was significantly correlated with body mass index (=0.25), visceral fat (=0.37), TC (=0.22), LDL (0.24), HDL (=-0.72), TG (=0.84), glucose (=0.32), systolic blood pressure (=0.22), and diastolic blood pressure (=0.28).
It indicated that AIP is associated with other CVD risk factors. Modification of lifestyle is strongly recommended.
血浆致动脉粥样硬化指数（AIP）被认为是预测心血管疾病（CVD）风险的最强标志物之一。本研究旨在确定AIP及其与其他CVD危险因素的关系。
本横断面研究在砂拉越一所公立大学的349名工作人员中进行。通过问卷调查、血液采样、人体测量和血压测量收集数据。使用IBM SPSS 20版软件进行数据分析。
共有349名受访者参与，其中大多数为女性（66.8%），年龄为38.5±7.82岁。近80%的受访者超重和肥胖，87.1%的人身体脂肪含量高或非常高，46.9%的人内脏脂肪异常。在AIP类别方面，发现8.9%处于中等风险，16.4%处于高风险。血脂升高显示总胆固醇（TC）为15.5%，低密度脂蛋白（LDL）为16.1%，甘油三酯（TG）为10.6%。AIP与体重指数（=0.25）、内脏脂肪（=0.37）、TC（=0.22）、LDL（0.24）、HDL（=-0.72）、TG（=0.84）、血糖（=0.32）、收缩压（=0.22）和舒张压（=0.28）显著相关。
这表明AIP与其他CVD危险因素相关。强烈建议改变生活方式。
