Flannery Marie, Stein Karen F, Dougherty David W, Mohile Supriya, Guido Joseph, Wells Nancy
University of Rochester.
Wilmot Cancer Institute.
Oncol Nurs Forum. 2018 Sep 1;45(5):619-630. doi: 10.1188/18.ONF.619-630.
To assess an intervention derived from self-regulation theory (SRT) to promote well-being for individuals with advanced lung cancer.
SAMPLE & SETTING: 45 adults with advanced lung cancer who were receiving chemotherapy at an ambulatory cancer center.
METHODS & VARIABLES: Participants were randomized to the intervention group or usual care control group. Feasibility assessment focused on recruitment, retention, design, methods, and fidelity. Outcome measures of quality of life, symptoms, and distress were collected at four time points. The main research variables were symptoms, quality of life, and distress.
The participation rate was 79%, and the retention rate was 62%. Participant loss was most often because of progressive disease and occurred early in the study. High fidelity was noted for delivery of the intervention as planned and outcome data collection by telephone. The mean number of interventions delivered was 5.5 of a planned 8. A high level of acceptability was reported for participants completing the intervention.
Although delivering the SRT-derived intervention with fidelity was possible, feasibility findings do not warrant intervention replication in this population.
评估一种源自自我调节理论（SRT）的干预措施，以促进晚期肺癌患者的幸福感。
45名在门诊癌症中心接受化疗的晚期肺癌成年患者。
参与者被随机分为干预组或常规护理对照组。可行性评估集中在招募、留存、设计、方法和保真度方面。在四个时间点收集生活质量、症状和痛苦程度的结果指标。主要研究变量为症状、生活质量和痛苦程度。
参与率为79%，留存率为62%。参与者流失最常见的原因是疾病进展，且发生在研究早期。按计划实施干预措施以及通过电话收集结果数据的保真度较高。实施的干预措施平均数量为计划的8次中的5.5次。据报告，完成干预的参与者接受度较高。
尽管有可能如实实施源自SRT的干预措施，但可行性研究结果不支持在该人群中重复进行干预。
