Oza Swapnil, Patel Kreta, Bhosale Satish, Mitra Ruchi, Gupta Rupam, Choudhary Divya
Department of Public Health Dentistry, Darshan Dental College and Hospital, Udaipur, Rajasthan, India.
Department of Oral Pathology and Microbiology, RR Dental College and Hospital, Udaipur, Rajasthan, India.
J Int Soc Prev Community Dent. 2018 Jul-Aug;8(4):354-360. doi: 10.4103/jispcd.JISPCD_54_18. Epub 2018 Jul 18.
The aim of the study is to determine the effect of chewing gum containing xylitol and sorbitol on mutans streptococci and count in saliva, plaque, and gingival health and to compare the efficacy of chewing gums.
The study was designed as a double-blinded randomized uncontrolled clinical trial with two parallel arms. A total of 80 students consented and completed the study. The test group (X) received corresponding pellets with xylitol and the control group (S) was given pellets containing sorbitol and maltitol three times daily for 30 days. Clinical scoring and saliva samples were collected at three different intervals, at baseline, 15, and 30 day of the study. The outcome measure was plaque index score, gingival index score, salivary mutans streptococci, and counts. Data collected were analyzed using Statistical Package for the Social Sciences (SPSS version 19.0).
There was no statistically significant difference between the mean of mutans streptococci count of test and control group at baseline and 15 day, but there was statistically highly significant difference ( = 0.00) between the mean of mutans streptococci count in test and control group on the 30 day. The mean of count, plaque index, and gingival index score between test and control group showed no statistically significant difference at baseline, 15 day, and 30 day.
The results suggest that only xylitol gum may interfere with the mutans streptococci composition and reduce it after continuous use of 30 days effectively as compared to sorbitol gum, but both the gums are equally effective on salivary , plaque, and gingiva at different intervals.
本研究旨在确定含有木糖醇和山梨醇的口香糖对变形链球菌及唾液、菌斑中的数量以及牙龈健康的影响,并比较口香糖的功效。
本研究设计为一项双盲随机非对照临床试验,有两个平行组。共有80名学生同意并完成了研究。试验组(X)接受含木糖醇的相应丸剂,对照组(S)每天三次服用含山梨醇和麦芽糖醇的丸剂,持续30天。在研究的基线、第15天和第30天这三个不同时间点收集临床评分和唾液样本。观察指标为菌斑指数评分、牙龈指数评分、唾液变形链球菌及数量。所收集的数据使用社会科学统计软件包(SPSS 19.0版)进行分析。
试验组和对照组在基线和第15天的变形链球菌平均计数之间无统计学显著差异,但在第30天,试验组和对照组的变形链球菌平均计数之间存在统计学高度显著差异(P = 0.00)。试验组和对照组之间的数量、菌斑指数和牙龈指数评分在基线、第15天和第30天均无统计学显著差异。
结果表明,与山梨醇口香糖相比,仅木糖醇口香糖在连续使用30天后可能会干扰变形链球菌的组成并有效降低其数量,但两种口香糖在不同时间点对唾液、菌斑和牙龈的作用效果相同。