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不同离子环境下银纳米颗粒的溶解行为与其对斑马鱼胚胎毒性之间的关系

The Relationship between Dissolution Behavior and the Toxicity of Silver Nanoparticles on Zebrafish Embryos in Different Ionic Environments.

作者信息

Lee Wang Sik, Kim Eungwang, Cho Hyun-Ju, Kang Taejoon, Kim Bongsoo, Kim Min Young, Kim Yong Sik, Song Nam Woong, Lee Jeong-Soo, Jeong Jinyoung

机构信息

Hazards Monitoring Bionano Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.

KRIBB School, University of Science and Technology, 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.

出版信息

Nanomaterials (Basel). 2018 Aug 23;8(9):652. doi: 10.3390/nano8090652.

DOI:10.3390/nano8090652
PMID:30142912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6165318/
Abstract

A silver nanoparticle is one of the representative engineered nanomaterials with excellent optical, electrical, antibacterial properties. Silver nanoparticles are being increasingly used for medical products, water filters, and cosmetics, etc. However, silver nanoparticles are known to cause adverse effects on the ecosystem and human health. To utilize silver nanoparticles with minimized negative effects, it is important to understand the behavior of silver nanoparticles released to the environment. In this study, we compared toxicity behaviors of citrate-stabilized silver nanoparticles with polyethylene glycol coated silver nanoparticles in two different ionic environments, which are aquatic environments for developing zebrafish embryo. Depending on the composition of the ionic environment, citrate-stabilized silver nanoparticles and polyethylene glycol coated silver nanoparticles exhibited different behaviors in dissolution, aggregation, or precipitation, which governed the toxicity of silver nanoparticles on zebrafish embryos.

摘要

银纳米颗粒是具有优异光学、电学、抗菌性能的代表性工程纳米材料之一。银纳米颗粒正越来越多地用于医疗产品、水过滤器和化妆品等。然而,已知银纳米颗粒会对生态系统和人类健康造成不利影响。为了在负面影响最小化的情况下利用银纳米颗粒,了解释放到环境中的银纳米颗粒的行为很重要。在本研究中,我们比较了柠檬酸盐稳定的银纳米颗粒和聚乙二醇包覆的银纳米颗粒在两种不同离子环境中的毒性行为,这两种环境是用于发育斑马鱼胚胎的水生环境。根据离子环境的组成,柠檬酸盐稳定的银纳米颗粒和聚乙二醇包覆的银纳米颗粒在溶解、聚集或沉淀方面表现出不同的行为,这些行为决定了银纳米颗粒对斑马鱼胚胎的毒性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c978/6165318/a4f6069f98ec/nanomaterials-08-00652-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c978/6165318/ecf2c691578e/nanomaterials-08-00652-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c978/6165318/48f1af9a53b2/nanomaterials-08-00652-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c978/6165318/2333a0d4066e/nanomaterials-08-00652-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c978/6165318/a4f6069f98ec/nanomaterials-08-00652-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c978/6165318/ecf2c691578e/nanomaterials-08-00652-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c978/6165318/48f1af9a53b2/nanomaterials-08-00652-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c978/6165318/2333a0d4066e/nanomaterials-08-00652-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c978/6165318/a4f6069f98ec/nanomaterials-08-00652-g004.jpg

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Behavior and Potential Impacts of Metal-Based Engineered Nanoparticles in Aquatic Environments.
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