Abshirini Maryam, Mahaki Behzad, Bagheri Fariba, Siassi Fereydoun, Koohdani Fariba, Sotoudeh Gity
Department of Community Nutrition, Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Int J Prev Med. 2018 Jul 30;9:64. doi: 10.4103/ijpvm.IJPVM_145_18. eCollection 2018.
Dietary phytochemical index (DPI) has introduced as an inexpensive method for quantifying the phytochemicals in foods. For the first time, this study was conducted to investigate the relationship between DPI and the risk of prediabetes.
Three hundred participants were assigned to 150 prediabetics (cases) and 150 healthy (controls) groups. Anthropometric values, fasting blood glucose, and 2-h oral glucose tolerance test (OGTT) were measured. The DPI was calculated based on data collected from 168-item validated food frequency questionnaire.
The sex-specific energy-adjusted DPI was inversely related to fasting blood glucose (FBG) and OGTT ( < 0.001). The odds ratio (OR) of prediabetes was assessed across sex-specific energy-adjusted DPI quartiles. After adjusting for body mass index, physical activity, education, dietary intake of energy, fiber, carbohydrate (% of energy), fat (% of energy), and protein (% of energy), the OR of prediabetes across the sex-specific energy-adjusted DPI quartiles decreased significantly (-trend < 0.001).
We found that higher DPI score is related to lower prediabetes OR. This simple method may be used for the improvement of dietary intake to prevent prediabetes.
膳食植物化学物质指数(DPI)已被引入作为一种量化食物中植物化学物质的廉价方法。本研究首次进行,旨在调查DPI与糖尿病前期风险之间的关系。
300名参与者被分为150名糖尿病前期患者(病例组)和150名健康者(对照组)。测量人体测量值、空腹血糖和2小时口服葡萄糖耐量试验(OGTT)。DPI是根据从168项经过验证的食物频率问卷收集的数据计算得出的。
按性别调整能量后的DPI与空腹血糖(FBG)和OGTT呈负相关(<0.001)。在按性别调整能量后的DPI四分位数中评估糖尿病前期的优势比(OR)。在调整了体重指数、身体活动、教育程度、能量、纤维、碳水化合物(能量百分比)、脂肪(能量百分比)和蛋白质(能量百分比)的膳食摄入量后,按性别调整能量后的DPI四分位数中糖尿病前期的OR显著降低(-趋势<0.001)。
我们发现较高的DPI得分与较低的糖尿病前期OR相关。这种简单的方法可用于改善膳食摄入量以预防糖尿病前期。