Smith Valeria, Foster Jennifer
Baylor College of Medicine Department of Pediatrics, Texas Children's Cancer and Hematology Center, Houston, TX 77030, USA.
Children (Basel). 2018 Aug 28;5(9):114. doi: 10.3390/children5090114.
Neuroblastoma is the most common extracranial solid tumor in children. One subset, high-risk neuroblastoma, is very difficult to treat and requires multi-modal therapy. Intensification of therapy has vastly improved survival rates, and research is focused on novel treatments to further improve survival rates. The current treatment schema is divided into three stages-induction, consolidation, and maintenance. This review serves as an overview of the current treatment for high-risk neuroblastoma and a glimpse at current research for future therapy.
神经母细胞瘤是儿童最常见的颅外实体瘤。其中一个亚组，即高危神经母细胞瘤，治疗非常困难，需要多模式治疗。强化治疗已极大提高了生存率，研究集中在新型治疗方法以进一步提高生存率。目前的治疗方案分为三个阶段——诱导、巩固和维持。本综述概述了高危神经母细胞瘤的当前治疗方法，并简要介绍了未来治疗的当前研究情况。
