Everett E D, Rham A E, Adaniya R, Stevens D L, McNitt T R
JAMA. 1977 Jul 25;238(4):319-21.
Thirty cases of Haemophilus influenzae pneumonia with clinical and laboratory features have previously been recorded in adults. During the past three years, we have examined 18 patients in whom this diagnosis was established by transtracheal aspirate or blood culture. Our study suggests that H influenzae, both typable and nontypable strains, is a more frequent cause of pneumonia in adults than previously appreciated. We found no clinical values that distinguished H influenzae pneumonia from other bacterial pneumonias. A properly performed Gram's stain of a transtracheal aspirate specimen is classical in its appearance and facilitates instritution of appropriate initial treatment. The emergence of both typable and nontypable organisms resistant to ampicillin makes it important that organisms be isolated from reliable samples for sensitivity testing. With appropriate therapy, the prognosis for patients with H influenzae pneumonia appears to be good.
此前已有30例具有临床和实验室特征的成人流感嗜血杆菌肺炎病例记录在案。在过去三年中,我们检查了18例通过经气管抽吸物或血培养确诊的患者。我们的研究表明,可分型和不可分型的流感嗜血杆菌菌株是成人肺炎比以往认识到的更常见病因。我们未发现能将流感嗜血杆菌肺炎与其他细菌性肺炎区分开来的临床指标。经气管抽吸物标本进行恰当的革兰氏染色,其外观典型,有助于开始适当的初始治疗。可分型和不可分型菌株对氨苄西林耐药的出现,使得从可靠样本中分离出细菌进行药敏试验很重要。经过适当治疗,流感嗜血杆菌肺炎患者的预后似乎良好。