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2
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本文引用的文献

1
In vitro cell migration as a model for delayed hypersensitivity.体外细胞迁移作为迟发型超敏反应的模型。
Proc Soc Exp Biol Med. 1962 Nov;111:514-21. doi: 10.3181/00379727-111-27841.
2
The physiological disposition of phenylbutazone (butazolidin) in man and a method for its estimation in biological material.保泰松（布他唑立丁）在人体中的生理处置及其在生物材料中的测定方法。
J Pharmacol Exp Ther. 1953 Nov;109(3):346-57.
3
Suppressive effects of indomethacin on crystal-induced inflammation in canine joints and on neutrophilic motility in vitro.吲哚美辛对犬关节晶体诱导的炎症及体外中性粒细胞运动的抑制作用。
J Pharmacol Exp Ther. 1967 Dec;158(3):546-53.
4
Studies on chemotaxis. X. Inhibition of chemotaxis of rabbit neutrophil polymorphonuclear leucocytes.趋化性研究。十、兔中性多形核白细胞趋化性的抑制
Int Arch Allergy Appl Immunol. 1968;34(5):513-20.
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Indomethacin inhibits the local Shwartzman reaction.吲哚美辛抑制局部施瓦茨曼反应。
Proc Soc Exp Biol Med. 1970 May;134(1):163-8. doi: 10.3181/00379727-134-34751.
6
[Distribution of indomethacin in blood and synovial fluid of patients with rheumatoid arthritis].[吲哚美辛在类风湿关节炎患者血液和滑液中的分布]
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7
A histopathological and pharmacological analysis of the mode of action of nonsteroidal anti-inflammatory drugs.非甾体抗炎药作用模式的组织病理学和药理学分析
J Pathol. 1971 Dec;105(4):239-56. doi: 10.1002/path.1711050403.
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Standardization of the leucocyte migration test.白细胞迁移试验的标准化
Int Arch Allergy Appl Immunol. 1973;45(1):308-21. doi: 10.1159/000231048.
9
Hydrocortisone and the migration of human leucocytes: an indirect effect mediated by mononuclear cells.氢化可的松与人类白细胞的迁移：由单核细胞介导的间接效应。
Clin Exp Immunol. 1973 Jul;14(3):417-26.
10
Indomethacin: plasma concentrations and protein binding in man.吲哚美辛：人体中的血浆浓度与蛋白质结合情况
Eur J Clin Pharmacol. 1972 Mar;4(2):119-24. doi: 10.1007/BF00562508.

非甾体抗炎药对人及大鼠外周血白细胞体外迁移的作用

Action of nonsteroidal, anti-inflammatory drugs on human and rat peripheral leucocyte migration in vitro.

作者信息

Brown K A, Collins A J

出版信息

Ann Rheum Dis. 1977 Jun;36(3):239-43. doi: 10.1136/ard.36.3.239.

DOI:10.1136/ard.36.3.239
PMID:301730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1006672/
Abstract

Using an in vitro system of cell migration from glass capillary tubes, the nonsteroidal, anti-inflammatory agents sodium salicylate, aspirin, ibuprofen, phenylbutazone, and indomethacin were shown to inhibit the migration of human peripheral leucocytes in a dose-related manner. This drug action was not confined to one species, as shown by the modification of rat peripheral leucocyte motility by sodium salicylate and aspirin. The relevance of the human findings to the clinical effectiveness of these agents is discussed.

摘要

利用玻璃毛细管中细胞迁移的体外系统，已表明非甾体抗炎药水杨酸钠、阿司匹林、布洛芬、保泰松和吲哚美辛以剂量相关的方式抑制人外周血白细胞的迁移。水杨酸钠和阿司匹林对大鼠外周血白细胞运动性的改变表明，这种药物作用并不局限于某一物种。文中讨论了这些人体研究结果与这些药物临床疗效的相关性。