Kim Jung-Hoon, Doh Eui-Jeong, Lee Guemsan
Division of Pharmacology, School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Department of Herbology, College of Korean Medicine, Wonkwang University, Iksan 54538, Republic of Korea.
Evid Based Complement Alternat Med. 2018 Aug 2;2018:4860371. doi: 10.1155/2018/4860371. eCollection 2018.
The rhizome of , which is a herbal medicine used for gastrointestinal therapeutics, has been categorized with rhizome or rhizome based on different therapeutic criteria in Korea, China, and Japan. In the present study, 61 , , and rhizomes were collected from Korea and China and were genetically identified by internal transcribed spacer sequencing analysis. Chromatographic profiles were obtained from high-performance liquid chromatography analysis of the methanol and hot-water extracts of rhizomes and chemical differentiation of the rhizomes was carried out using chemometric statistical analyses such as principal component analysis, hierarchical clustering analysis, and Pearson's correlation coefficient analysis. The results from chromatographic profiles and chemometric analyses demonstrate that rhizomes showed apparent chemical differences from and rhizomes in the methanol extracts. In contrast, no clear distinction was apparent for the hot-water extracts of rhizomes, especially rhizomes. These results indicate that there is a clear chemical difference between and rhizomes; however, the chemical diversity of rhizome shows different chemical relationships with or rhizome, dependent on the chemical features.
作为用于胃肠道治疗的草药，[植物名称]的根茎在韩国、中国和日本根据不同的治疗标准被归类为[根茎名称1]根茎或[根茎名称2]根茎。在本研究中，从韩国和中国收集了61份[植物名称]、[根茎名称1]和[根茎名称2]根茎，并通过内部转录间隔区测序分析进行了基因鉴定。通过对[植物名称]根茎的甲醇提取物和热水提取物进行高效液相色谱分析获得色谱图，并使用主成分分析、层次聚类分析和皮尔逊相关系数分析等化学计量统计分析方法对根茎进行化学区分。色谱图和化学计量分析结果表明，[植物名称]根茎在甲醇提取物中与[根茎名称1]和[根茎名称2]根茎表现出明显的化学差异。相比之下，[植物名称]根茎的热水提取物，尤其是[根茎名称2]根茎的热水提取物，没有明显的区别。这些结果表明，[植物名称]和[根茎名称1]或[根茎名称2]根茎之间存在明显的化学差异；然而，[植物名称]根茎的化学多样性根据化学特征与[根茎名称1]或[根茎名称2]根茎表现出不同的化学关系。
