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腕戴式酒精生物传感器:优势、局限性及未来方向。

Wrist-worn alcohol biosensors: Strengths, limitations, and future directions.

机构信息

Department of Epidemiology, the University of Florida, Gainesville, FL, United States.

Department of Psychiatry and Behavioral Neuroscience, the University of Chicago, Chicago, IL, United States.

出版信息

Alcohol. 2019 Dec;81:83-92. doi: 10.1016/j.alcohol.2018.08.013. Epub 2018 Sep 1.

Abstract

Wearable alcohol biosensors have emerged as a valuable tool for noninvasive, objective, and continuous monitoring of alcohol consumption. However, to date their research and clinical applications have been limited by several factors including large size, high cost, and social stigma. In contrast, recently developed wrist-worn alcohol biosensors are smaller, less expensive, and may be more acceptable for daily use. However, these devices are at the prototype phase and have just begun to be tested for research applications. In this paper, we describe our experiences with two prototypes of these new wrist-worn alcohol biosensors (i.e., Quantac Tally and BACtrack Skyn) and their associated smartphone applications in both a controlled laboratory setting and the real-world environment. Our preliminary experiences with these devices highlight their advantages including comfort, high participant acceptability, and good compliance. However, there are various limitations that should be addressed prior to future research applications of these biosensors, including large interpersonal variations in transdermal alcohol readings, lack of immediately applicable data analysis/interpretation software, and poor battery life after a few months. More research is also needed to further validate the new biosensors, and investigate individual (e.g., skin thickness, gender differences) and environmental factors (e.g., humidity, temperature) contributing to the variations in transdermal alcohol readings measured by wrist-worn alcohol biosensors.

摘要

可穿戴酒精生物传感器已成为一种用于非侵入性、客观和连续监测酒精摄入的有价值的工具。然而,迄今为止,它们的研究和临床应用受到了几个因素的限制,包括尺寸大、成本高和社会耻辱感。相比之下,最近开发的腕戴式酒精生物传感器体积更小、成本更低,可能更适合日常使用。然而,这些设备处于原型阶段,刚刚开始用于研究应用的测试。在本文中,我们描述了我们在两种新型腕戴式酒精生物传感器(即 Quantac Tally 和 BACtrack Skyn)及其相关智能手机应用程序的两个原型在受控实验室环境和真实环境中的使用经验。我们对这些设备的初步经验突出了它们的优势,包括舒适度、高参与者接受度和良好的依从性。然而,在未来的生物传感器研究应用之前,还存在各种需要解决的限制,包括经皮酒精读数的人际间差异较大、缺乏立即适用的数据分析/解释软件以及几个月后电池寿命差。还需要更多的研究来进一步验证新的生物传感器,并研究个体(例如,皮肤厚度、性别差异)和环境因素(例如,湿度、温度)对腕戴式酒精生物传感器测量的经皮酒精读数变化的影响。

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