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腕戴式酒精生物传感器:在行为研究中的应用和可用性。

Wrist-worn alcohol biosensors: Applications and usability in behavioral research.

机构信息

Department of Epidemiology, The University of Florida, Gainesville, FL, United States.

Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, IL, United States.

出版信息

Alcohol. 2021 May;92:25-34. doi: 10.1016/j.alcohol.2021.01.007. Epub 2021 Feb 18.

Abstract

Wrist-worn alcohol biosensor technology has developed rapidly in recent years. These devices are light, easy to wear, relatively inexpensive, and resemble commercial fitness trackers. As a result, they may be more suitable for a wide range of clinical and research applications. In this paper, we describe three pilot projects examining the associations between reported drinking behavior and transdermal alcohol concentration (TAC) derived from a new, wrist-worn alcohol biosensor (BACtrack Skyn) in diverse participant groups and settings. Study 1 (N = 3) compared Skyn-derived TAC with that from an ankle-worn alcohol sensor (SCRAM CAM) and breath alcohol concentration (BrAC) in a laboratory setting. Study 2 (N = 10) compared Skyn TAC with BrAC during a naturalistic drinking episode in the field. Study 3 (N = 12) used the Skyn to monitor alcohol use in the field for 2 weeks. Studies 2 and 3 also collected usability and acceptability data from participants. The results of Study 1 showed that the Skyn produced a TAC curve that closely resembled that of the validated SCRAM CAM anklet. In Study 2, Skyn detected drinking for all 10 participants (peak BrAC range: 0.02-0.21) with an average delay of 35.6 ± 10.2 min after the start of self-reported drinking. In Study 3, Skyn reliably recorded continuous TAC data showing multiple drinking episodes over the monitoring period. Participants in Studies 2 and 3 both reported Skyn as highly acceptable. Collectively, the results of these pilot studies show that the Skyn was able to reliably detect drinking events in the laboratory and natural environments. We offer suggestions for further refinements of alcohol biosensors and accompanying analytic software that may facilitate adoption of these devices as cost-effective, user-friendly, and reliable tools to passively and accurately assess alcohol use in the field.

摘要

近年来,腕戴式酒精生物传感器技术发展迅速。这些设备轻巧、易于佩戴、相对便宜,且类似于商业健身追踪器。因此,它们可能更适用于广泛的临床和研究应用。在本文中,我们描述了三个试点研究,这些研究检查了在不同参与者群体和环境中,新型腕戴式酒精生物传感器(BACtrack Skyn)报告的饮酒行为与经皮酒精浓度(TAC)之间的关联。研究 1(N=3)比较了 Skyn 衍生的 TAC 与脚踝佩戴式酒精传感器(SCRAM CAM)和呼吸酒精浓度(BrAC)在实验室环境中的结果。研究 2(N=10)比较了 Skyn 在现场自然饮酒事件中的 TAC 与 BrAC。研究 3(N=12)使用 Skyn 在现场监测 2 周的酒精使用情况。研究 2 和 3 还从参与者那里收集了可用性和可接受性数据。研究 1 的结果表明,Skyn 产生的 TAC 曲线与经过验证的 SCRAM CAM 踝带非常相似。在研究 2 中,Skyn 检测到所有 10 名参与者的饮酒情况(峰值 BrAC 范围:0.02-0.21),自报告饮酒开始后平均延迟 35.6±10.2 分钟。在研究 3 中,Skyn 可靠地记录了连续的 TAC 数据,显示在监测期间发生了多次饮酒事件。研究 2 和 3 的参与者都报告 Skyn 非常易于接受。总的来说,这些试点研究的结果表明,Skyn 能够可靠地检测实验室和自然环境中的饮酒事件。我们为进一步改进酒精生物传感器及其伴随的分析软件提供了建议,这可能有助于这些设备作为经济高效、用户友好且可靠的工具被采用,以被动和准确地评估现场的酒精使用情况。

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