Rheumatology Division, Applied Physiology and Nutrition Research Group, School of Physical Education and Sport, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.
University of Sao Paulo, São Paulo, SP, Brazil.
Amino Acids. 2019 Jan;51(1):83-96. doi: 10.1007/s00726-018-2643-2. Epub 2018 Sep 4.
The effects of β-alanine (BA) and sodium bicarbonate (SB) on energy metabolism during work-matched high-intensity exercise and cycling time-trial performance were examined in 71 male cyclists. They were randomised to receive BA + placebo (BA, n = 18), placebo + SB (SB, n = 17), BA + SB (BASB, n = 19), or placebo + placebo (PLA, n = 18). BA was supplemented for 28 days (6.4 g day) and SB (0.3 g kg) ingested 60 min before exercise on the post-supplementation trial. Dextrose and calcium carbonate were placebos for BA and SB, respectively. Before (PRE) and after (POST) supplementation, participants performed a high-intensity intermittent cycling test (HICT-110%) consisting of four 60-s bouts at 110% of their maximal power output (60-s rest between bouts). The estimated contribution of the energy systems was calculated for each bout in 39 of the participants (BA: n = 9; SB: n = 10; BASB: n = 10, PLA: n = 10). Ten minutes after HICT-110%, cycling performance was determined in a 30-kJ time-trial test in all participants. Both groups receiving SB increased estimated glycolytic contribution in the overall HICT-110%, which approached significance (SB: + 23%, p = 0.068 vs. PRE; BASB: + 18%, p = 0.059 vs. PRE). No effects of supplementation were observed for the estimated oxidative and ATP-PCr systems. Time to complete 30 kJ was not significantly changed by any of the treatments, although a trend toward significance was shown in the BASB group (p = 0.06). We conclude that SB, but not BA, increases the estimated glycolytic contribution to high-intensity intermittent exercise when total work done is controlled and that BA and SB, either alone or in combination, do not improve short-duration cycling time-trial performance.
研究了 β-丙氨酸（BA）和碳酸氢钠（SB）对 71 名男性自行车手进行高强度工作匹配运动和计时赛表现的能量代谢的影响。他们被随机分配接受 BA+安慰剂（BA，n=18）、安慰剂+SB（SB，n=17）、BA+SB（BASB，n=19）或安慰剂+安慰剂（PLA，n=18）。BA 补充 28 天（每天 6.4 克），SB（0.3 克/公斤）在补充后试验前 60 分钟摄入。葡萄糖和碳酸钙分别是 BA 和 SB 的安慰剂。在补充前后（PRE），参与者进行了高强度间歇自行车测试（HICT-110%），由四个 60 秒的回合组成，每个回合的强度为最大输出功率的 110%（回合之间休息 60 秒）。计算了每个回合中 39 名参与者的能量系统的估计贡献（BA：n=9；SB：n=10；BASB：n=10，PLA：n=10）。在 HICT-110%后 10 分钟，所有参与者都进行了 30 kJ 计时赛测试，以确定他们的自行车表现。接受 SB 的两组都增加了整个 HICT-110%中估计的糖酵解贡献，这一变化接近显著（SB：增加 23%，p=0.068 与 PRE 相比；BASB：增加 18%，p=0.059 与 PRE 相比）。补充对估计的氧化和 ATP-PCr 系统没有影响。任何处理都没有显著改变完成 30 kJ 的时间，尽管 BASB 组显示出显著趋势（p=0.06）。我们得出结论，当控制总工作量时，SB 而非 BA 会增加高强度间歇运动的估计糖酵解贡献，而 BA 和 SB 单独或联合使用都不会提高短时间自行车计时赛的表现。
