Liang Wenxuan, Hall Gunnsteinn, Li Xingde
Opt Express. 2018 Sep 3;26(18):22877-22893. doi: 10.1364/OE.26.022877.
The emerging fiber-optic two-photon endomicroscopy technology holds a strong promise for enabling translational applications of nonlinear optical imaging. Effective femtosecond pulse dispersion management is critical for achieving high-quality imaging. Here we report systematic analyses and performance characterization of a dual-fiber spectro-temporal dispersion management scheme involving a grating pair as the pulse stretcher. Compared with conventional linear-only compensation, the grating-based spectro-temporal compensation also takes into account nonlinear effects and enhances the two-photon signal by ~3-fold as experimentally demonstrated. Numerical simulations were carried out to systematically investigate the influence of several key design parameters on the overall compensation efficacy. Furthermore, comprehensive performance comparison with an ideal grism-pair counterpart reveals that a grating-pair stretcher affords much higher power throughput and thus is preferable for portable endomicroscopy systems with limited laser source power.
新兴的光纤双光子内窥技术在实现非线性光学成像的转化应用方面具有很大的前景。有效的飞秒脉冲色散管理对于实现高质量成像至关重要。在此，我们报告了一种双光纤光谱 - 时间色散管理方案的系统分析和性能表征，该方案采用光栅对作为脉冲展宽器。与传统的仅线性补偿相比，基于光栅的光谱 - 时间补偿还考虑了非线性效应，并且如实验所示，将双光子信号增强了约3倍。进行了数值模拟，以系统地研究几个关键设计参数对整体补偿效果（功效）的影响。此外，与理想的光栅棱镜对进行的全面性能比较表明，光栅对展宽器具有更高的功率通过率，因此对于激光源功率有限的便携式内窥系统而言更为可取。
