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关于医用大麻对严重精神疾病患者影响的重要问题。

Important Questions About the Impact of Medical Marijuana on People With Serious Mental Illness.

机构信息

Dr. Brunette, Dr. Borodovsky, and Dr. Budney are with the Department of Psychiatry, Geisel School of Medicine, Dartmouth-Hitchcock, Concord, New Hampshire. Dr. Myers is with Northern Human Services, Conway, New Hampshire.

出版信息

Psychiatr Serv. 2018 Nov 1;69(11):1181-1183. doi: 10.1176/appi.ps.201800210. Epub 2018 Sep 6.

Abstract

Many people are interested in using marijuana for therapeutic purposes as legalization expands across the country. The impact of marijuana depends upon the consumed potency and dose of its major psychoactive components, tetrahydrocannabinol and cannabidiol, which have very different psychiatric effects. This Open Forum discusses what is known about the impact of these marijuana constituents on people with serious mental illnesses, who may experience many adverse effects and more easily develop addiction with marijuana use. As use of medical marijuana increases, mental health clinicians can help prevent or address adverse effects by informing themselves and others about marijuana's effects and by coordinating with marijuana prescribers.

摘要

随着大麻合法化在全国范围内的扩展,许多人对将大麻用于治疗目的很感兴趣。大麻的影响取决于其主要精神活性成分四氢大麻酚和大麻二酚的摄入量和剂量,这两种成分具有非常不同的精神影响。本公开论坛讨论了已知的这些大麻成分对患有严重精神疾病的人的影响,这些人可能会经历许多不良反应,并且更容易因使用大麻而产生成瘾。随着医用大麻使用的增加,精神健康临床医生可以通过了解大麻的作用并与大麻处方者协调,来帮助预防或解决不良反应。

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本文引用的文献

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Cannabis-associated psychosis: Neural substrate and clinical impact.大麻相关精神病:神经基础及其临床影响。
Neuropharmacology. 2017 Sep 15;124:89-104. doi: 10.1016/j.neuropharm.2017.06.018. Epub 2017 Jun 17.
10
The endocannabinoid system and the brain.内源性大麻素系统与大脑。
Annu Rev Psychol. 2013;64:21-47. doi: 10.1146/annurev-psych-113011-143739. Epub 2012 Jul 12.

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