Institute for Skeletal Aging & Orthopedic Surgery, Hallym University-Chuncheon Sacred Heart Hospital, Chuncheon-si 24252, Gangwon-do, Korea.
Molecules. 2018 Sep 5;23(9):2268. doi: 10.3390/molecules23092268.
contains several alkaloids that are bioactive agents of therapeutic value. We propose an eco-friendly method to synthesize biocompatible silver nanoparticles (AgNPs) using the aqueous extract of . Silver ions were reduced to AgNPs using the aqueous extract of , indicating that can be used for the biosynthesis of AgNPs. The time and the concentration required for conversion of silver ions into AgNPs was optimized using UV-absorbance spectroscopy and inductively coupled plasma spectroscopy (ICP). Biosynthesized AgNPs showed a distinct UV-Visible absorption peak at 420 nm. ICP analysis showed that the time required for the completion of biosynthesis was around 20 min. Microscopic images showed that nanoparticles synthesized were of spherical shape and the average diameter of biosynthesized AgNPs was less than 30 nm. XRD analysis also confirmed the size of AgNps and revealed their crystalline nature. The interaction of AgNPs with phytochemicals present in extract was observed in FTIR analysis. The antimicrobial property of AgNPs was evaluated using turbidity measurements. -mediated biosynthesized AgNPs showed significant anti-bacterial activities against and that are commonly involved in various types of infections, indicating their potential as an effective anti-bacterial agent.
含有几种具有治疗价值的生物活性生物碱。我们提出了一种使用 的水提物来合成生物相容性银纳米粒子（AgNPs）的环保方法。银离子被 的水提物还原为 AgNPs，这表明 可用于 AgNPs 的生物合成。使用紫外吸收光谱和电感耦合等离子体光谱（ICP）优化了将银离子转化为 AgNPs 的时间和浓度。生物合成的 AgNPs 在 420nm 处显示出明显的紫外可见吸收峰。ICP 分析表明，生物合成完成所需的时间约为 20 分钟。显微镜图像显示，合成的纳米粒子为球形，生物合成的 AgNPs 的平均直径小于 30nm。XRD 分析也证实了 AgNps 的尺寸并揭示了其晶体性质。在 FTIR 分析中观察到 AgNPs 与 提取物中存在的植物化学物质的相互作用。使用浊度测量评估了 AgNPs 的抗菌性能。 -介导的生物合成 AgNPs 对 和 表现出显著的抗菌活性，这两种菌通常涉及各种类型的感染，表明它们具有作为有效抗菌剂的潜力。
