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来自革兰氏阳性球菌的卡那霉素抗性决定因子aphA-3在弯曲杆菌属中的传播。

Dispersal in Campylobacter spp. of aphA-3, a kanamycin resistance determinant from gram-positive cocci.

作者信息

Papadopoulou B, Courvalin P

机构信息

Unité des Agents Antibactériens, Institut Pasteur, Paris, France.

出版信息

Antimicrob Agents Chemother. 1988 Jun;32(6):945-8. doi: 10.1128/AAC.32.6.945.

DOI:10.1128/AAC.32.6.945
PMID:3046485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC172315/
Abstract

DNA annealing studies indicated that kanamycin resistance in Campylobacter strains from various geographical areas is encoded by a gene structurally related to aphA-3 of gram-positive cocci. This finding confirms the transfer of genetic material between gram-positive and gram-negative bacteria under natural conditions.

摘要

DNA退火研究表明，来自不同地理区域的弯曲杆菌菌株中的卡那霉素抗性由一个基因编码，该基因在结构上与革兰氏阳性球菌的aphA-3相关。这一发现证实了在自然条件下革兰氏阳性菌和革兰氏阴性菌之间遗传物质的转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/652e/172315/9ab8df7b37b6/aac00085-0175-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/652e/172315/3b1705d6c6c7/aac00085-0174-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/652e/172315/436dcdf20c93/aac00085-0174-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/652e/172315/9ab8df7b37b6/aac00085-0175-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/652e/172315/3b1705d6c6c7/aac00085-0174-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/652e/172315/436dcdf20c93/aac00085-0174-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/652e/172315/9ab8df7b37b6/aac00085-0175-a.jpg

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本文引用的文献

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Campylobacter enteritis.弯曲杆菌肠炎
N Engl J Med. 1981 Dec 10;305(24):1444-52. doi: 10.1056/NEJM198112103052404.
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Characterization of tetracycline resistance plasmids from Campylobacter jejuni and Campylobacter coli.空肠弯曲菌和结肠弯曲菌四环素抗性质粒的特性分析。
Antimicrob Agents Chemother. 1983 Dec;24(6):930-5. doi: 10.1128/AAC.24.6.930.
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Nucleotide sequence of the Streptococcus faecalis plasmid gene encoding the 3'5"-aminoglycoside phosphotransferase type III.粪肠球菌质粒基因的核苷酸序列，该基因编码III型3'5"-氨基糖苷磷酸转移酶
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Characterization of two plasmids from Campylobacter jejuni isolates that carry the aphA-7 kanamycin resistance determinant.对空肠弯曲菌分离株中携带aphA - 7卡那霉素抗性决定簇的两种质粒的特性分析。
Antimicrob Agents Chemother. 1992 Apr;36(4):712-6. doi: 10.1128/AAC.36.4.712.
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Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5.转座子Tn5中新霉素磷酸转移酶基因的核苷酸序列及精确定位。
Gene. 1982 Oct;19(3):327-36. doi: 10.1016/0378-1119(82)90023-3.
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Nucleotide sequence of the kanamycin resistance transposon Tn903.卡那霉素抗性转座子Tn903的核苷酸序列。
J Mol Biol. 1981 Apr 5;147(2):217-26. doi: 10.1016/0022-2836(81)90438-1.
6
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