Papadopoulou B, Courvalin P
Unité des Agents Antibactériens, Institut Pasteur, Paris, France.
Antimicrob Agents Chemother. 1988 Jun;32(6):945-8. doi: 10.1128/AAC.32.6.945.
DNA annealing studies indicated that kanamycin resistance in Campylobacter strains from various geographical areas is encoded by a gene structurally related to aphA-3 of gram-positive cocci. This finding confirms the transfer of genetic material between gram-positive and gram-negative bacteria under natural conditions.
DNA退火研究表明,来自不同地理区域的弯曲杆菌菌株中的卡那霉素抗性由一个基因编码,该基因在结构上与革兰氏阳性球菌的aphA-3相关。这一发现证实了在自然条件下革兰氏阳性菌和革兰氏阴性菌之间遗传物质的转移。