Zimelewicz Oberman Dan, Patrucco Liliana, Cuello Oderiz Carolina
University Institute, Hospital Italiano de Buenos Aires, Potosí 1199, Argentina.
Department of Neurology, Hospital Italiano de Buenos Aires, Potosí 1199, Argentina.
Diseases. 2018 Aug 31;6(3):75. doi: 10.3390/diseases6030075.
Cryptococcal meningitis is a life-threatening condition caused by a fungal pathogen, , that can infect both immunosuppressed and immunocompetent hosts. It is an important cause of morbidity and mortality in severely immunodeficient patients. However, in an immunocompetent patient it represents a diagnostic challenge, mainly because it is extremely rare, but also because of its nonspecific clinical manifestation. Neurovascular involvement in cryptococcal meningitis is rare and not well known and only few reports have described this association. We describe a cryptococcal meningitis in an immunocompetent patient associated with central nervous system vasculitis.
隐球菌性脑膜炎是一种由真菌病原体引起的危及生命的疾病,可感染免疫功能低下和免疫功能正常的宿主。它是严重免疫缺陷患者发病和死亡的重要原因。然而,在免疫功能正常的患者中,它是一个诊断难题,主要是因为它极为罕见,还因其临床表现不具有特异性。隐球菌性脑膜炎累及神经血管的情况罕见且鲜为人知,仅有少数报告描述过这种关联。我们描述了一例免疫功能正常的患者发生的隐球菌性脑膜炎,该病例伴有中枢神经系统血管炎。