连接组到行为：在细胞分辨率下的建模。
Connectome to behaviour: modelling at cellular resolution.
机构信息
OpenWorm Foundation, Boston, MA, USA
OpenWorm Foundation, Boston, MA, USA.
出版信息
Philos Trans R Soc Lond B Biol Sci. 2018 Sep 10;373(1758):20170366. doi: 10.1098/rstb.2017.0366.
Abstract
It has been 30 years since the 'mind of the worm' was published in (White 1986 , 1-340). Predicting ' behaviour from its wiring diagram has been an enduring challenge since then. This special theme issue of combines research from neuroscientists, physicists, mathematicians and engineers to discuss advances in neural activity imaging, behaviour quantification and multiscale simulations, and how they are bringing the goal of whole-animal modelling at cellular resolution within reach.This article is part of a discussion meeting issue 'Connectome to behaviour: modelling at cellular resolution'.
摘要
自 1986 年怀特的《蠕虫的思维》一文发表以来已经过去了 30 年。从那时起，人们一直面临着从其布线图预测“行为”的挑战。本期 特刊汇集了神经科学家、物理学家、数学家和工程师的研究成果，讨论了神经活动成像、行为量化和多尺度模拟方面的进展，以及它们如何使在细胞分辨率下进行整体动物建模的目标成为可能。本文是“从连接组到行为：在细胞分辨率下进行建模”的讨论会议特刊的一部分。
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