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绿茶及其成分抗癌的可能机制。

Possible Mechanisms of Green Tea and Its Constituents against Cancer.

机构信息

Department of Gastroenterology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.

Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.

出版信息

Molecules. 2018 Sep 7;23(9):2284. doi: 10.3390/molecules23092284.

Abstract

A number of epidemiological, clinical, and experimental researches have indicated that administration of green tea appears to have anti-cancer activity. According to findings of laboratory cell culture studies, a diverse mechanism has been observed underlying the effects of green tea catechins against cancer. These mechanisms include anti-oxidant activity, cell cycle regulation, receptor tyrosine kinase pathway inhibition, immune system modulation, and epigenetic modification control. This review discusses the results of these studies to provide more insight into the effects of green tea administration on cancers observed to date in this research field.

摘要

许多流行病学、临床和实验研究表明,饮用绿茶似乎具有抗癌活性。根据实验室细胞培养研究的结果,观察到绿茶儿茶素对癌症的作用具有多种机制。这些机制包括抗氧化活性、细胞周期调节、受体酪氨酸激酶途径抑制、免疫系统调节和表观遗传修饰控制。本文综述了这些研究的结果,以期更深入了解该研究领域迄今为止观察到的绿茶干预对癌症的影响。

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